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Your search keyword '"Zeng, Baitao"' showing total 3 results
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3 results on '"Zeng, Baitao"'

1. A General-Purpose Device for Interaction with LLMs

Author

Xu, Jiajun, Wang, Qun, Cao, Yuhang, Zeng, Baitao, and Liu, Sicheng

Subjects
Computer Science - Hardware Architecture, Computer Science - Artificial Intelligence, Computer Science - Computation and Language, Computer Science - Human-Computer Interaction, Computer Science - Robotics
Abstract

This paper investigates integrating large language models (LLMs) with advanced hardware, focusing on developing a general-purpose device designed for enhanced interaction with LLMs. Initially, we analyze the current landscape, where virtual assistants and LLMs are reshaping human-technology interactions, highlighting pivotal advancements and setting the stage for a new era of intelligent hardware. Despite substantial progress in LLM technology, a significant gap exists in hardware development, particularly concerning scalability, efficiency, affordability, and multimodal capabilities. This disparity presents both challenges and opportunities, underscoring the need for hardware that is not only powerful but also versatile and capable of managing the sophisticated demands of modern computation. Our proposed device addresses these needs by emphasizing scalability, multimodal data processing, enhanced user interaction, and privacy considerations, offering a comprehensive platform for LLM integration in various applications.

Published
2024

2. Reevaluating the splice-altering variant in TECTA as a cause of nonsyndromic hearing loss DFNA8/12 by functional analysis of RNA

Author

Yang, Yan, primary, Luo, Haiyan, additional, Pan, Lijuan, additional, Feng, Chuanxin, additional, Guo, Zhen, additional, Zou, Yongyi, additional, Zeng, Baitao, additional, Huang, Shuhui, additional, Yuan, Huizhen, additional, Wu, Ping, additional, Liu, Danping, additional, Dan, Yi, additional, Xiao, Junfang, additional, Li, XinYu, additional, Chen, ZhongFa, additional, Zeng, Xiao Ni, additional, Jiang, XiangLong, additional, Yang, Bicheng, additional, Liu, Yuhe, additional, and Liu, Yanqiu, additional

Published
2024
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3. Prenatal chromosomal microarray analysis in a large Chinese cohort of fetuses with congenital heart defects: a single center study.

Author

Lu, Qing, Luo, Laipeng, Zeng, Baitao, Luo, Haiyan, Wang, Xianjin, Qiu, Lijuan, Yang, Yan, Feng, Chuanxin, Zhou, Jihui, Hu, Yanling, Huang, Tingting, Ma, Pengpeng, Huang, Ting, Xie, Kang, Yuan, Huizhen, Huang, Shuhui, Yang, Bicheng, Zou, Yongyi, and Liu, Yanqiu

Subjects
CONGENITAL heart disease, GENETIC counseling, ABORTION, HUMAN abnormalities, PRENATAL diagnosis
Abstract

Background and objectives: Congenital heart defect (CHD) is one of the most common birth defects. The aim of this cohort study was to evaluate the prevalence of chromosomal abnormalities and the clinical utility of chromosomal microarray analysis (CMA) in fetuses with different types of CHD, aiming to assist genetic counseling and clinical decision-making. Methods: In this study, 642 fetuses with CHD were enrolled from a single center over a six-year period (2017–2022). Both conventional karyotyping and CMA were performed simultaneously on these fetuses. Results: The diagnostic yield of CMA in fetuses with CHD in our study was 15.3% (98/642). Our findings revealed a significant increase in the diagnostic yield of CMA compared to karyotyping in fetuses with CHD. Among CHD subgroups, the diagnostic yields were high in complex CHD (34.9%), conotruncal defects (28.6%), right ventricular outflow tract obstructive defects (RVOTO) (25.9%), atrioventricular septal defects (AVSD) (25.0%) and left ventricular outflow tract obstructive defects (LVOTO) (24.1%), while those in other CHD (10.6%) and septal defects (10.9%) were relatively low. The overall detection rate of clinically significant chromosomal abnormalities was significantly higher in the non-isolated CHD group compared to the isolated CHD group (33.1% vs. 9.9%, P < 0.0001). Interestingly, numerical chromosomal abnormalities were more likely to occur in the non-isolated CHD group than in the isolated CHD group (20.3% vs. 2.0%, P < 0.0001). The rate of termination of pregnancy (TOP)/Still birth in the non-isolated CHD group was significantly higher than that in the isolated CHD group (40.5% vs. 20.6%, P < 0.0001). Compared to the isolated CHD group, the detection rate of clinically significant chromosomal abnormalities was significantly higher in the group of CHD with soft markers (35.6% vs. 9.9%, P < 0.0001) and in the group of CHD with additional structural anomalies (36.1% vs. 9.9%, P < 0.0001). Conclusions: CMA is a reliable and high-resolution technique that should be recommended as the front-line test for prenatal diagnosis of fetuses with CHD. The prevalence of chromosomal abnormalities varies greatly among different subgroups of CHD, and special attention should be given to prenatal non-isolated cases of CHD, especially those accompanied by additional structural anomalies or soft markers. [ABSTRACT FROM AUTHOR]

Published
2024
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