Search

Diabetic foot is one of the most severe complications of diabetes. It is caused by high blood sugar, resulting in combined neuropathy and various degrees of peripheral vascular disease, leading to local microcirculation disorders. This condition can trigger infections, ulcers, and deep tissue damage in the lower limbs. In severe cases, gangrene may occur, leading to amputation. Therefore, timely microcirculation monitoring of the feet in diabetic patients can help detect early blood supply issues. Prompt and effective intervention and treatment for diabetic patients with microcirculation disorders in the feet can prevent the occurrence and development of diabetic foot. Physical factor therapy utilizes various forms of physical energy to induce reactions in the body, such as dilating blood vessels, increasing blood flow, and promoting tissue blood supply. Simultaneously, it stimulates nerves and muscles, aiding in improving nerve conduction and promoting nerve regeneration. This helps prevent and improve microcirculation disorders in diabetic feet. This article outlines the microcirculation disorders in diabetic feet, along with monitoring and treatment methods. It focuses on the principles and efficacy of common physical factor methods for microcirculation intervention, as well as research advancements in their clinical application for diabetic foot. This information serves as a reference for the treatment and adjunctive research of diabetic foot.

Background Multicompartmental osteoarthritis (MOA) in both tibiofemoral and patellofemoral joints is a more commonly occurring, but neglected, clinical condition, and we examined the short-term safety and efficacy of autologous stromal vascular fractions (SVFs) for MOA using a single-blind, prospective, randomized, placebo-controlled trial. Methods Seventy MOA patients were recruited and randomly assigned to the SVF group and hyaluronic acid (HA) group (control group). The scores of visual analog scale, the Western Ontario and McMaster University Osteoarthritis Index, and the Samsung Medical Center patellofemoral scoring system were assessed and compared between the two groups 3, 6 and 12 months after treatment. Results The SVF group had significantly better visual analog scale scores than the HA group at 6 and 12 months after treatment and had better Western Ontario and McMaster University Osteoarthritis Index scores than the HA group only at 6 months after treatment. For Samsung Medical Center patellofemoral scoring system of the patellofemoral joint, the SVF group had significantly better scores than the control group at all postoperative time points. The proportion of patients whose visual analog scale and Western Ontario and McMaster University Osteoarthritis Index scores were above the minimal clinically important improvement was higher in the SVF group than in the HA group in the majority of assessments. The improvement of bone marrow by SVF treatment was significantly better than that of the HA group as observed by pre- and postoperative Magnetic resonance imaging (MRI). Conclusions Multiple intra-articular injection of autologous SVF reduces pain and improves function in the short term in patients with early or midstage MOA. However, there was heterogeneity in the improvement of overall knee and isolated patellofemoral joint after treatment.   What is already known on this topic   Knee osteoarthritis (KOA) is the most common type of degenerative joint disease in humans. Autologous stromal vascular fraction (SVF) has been gradually applied to the treatment of KOA due to its multidifferentiation and ease of access. However, most current studies have focused on the tibiofemoral (TF) joint, and we know little about the performance of SVF in multiple compartments of the knee, including the patellofemoral (PF) joint. What this study adds   Multiple intra-articular injections of SVF are safe and effective for MOA in short-term (within 12 months) follow-up. Patients with MOA appear to have different feedback on treatment in different compartments of the knee, including the PF and TF joints, after SVF treatment. How this study might affect research, practice, or policy   More research is needed to clarify the appropriate dosage and injection schedule of SVF to standardize its clinical use. The rational selection of the indications for SVF in the treatment of KOA needs to be done more carefully when OA affects multiple compartments of the knee joint. [ABSTRACT FROM AUTHOR]

This work presents a beam element approach for the modeling and high-efficiency simulation of mechanical properties of 2.5D woven composite. For the beam element model, a technical scheme for the parametric modeling of 2.5D woven fabrics was produced. Considering the constraint relationship between the matrix and the fibers, we proposed a method for creating matrix beam elements. Then, a beam element solver was compiled to simulate the mechanical properties of the 2.5D woven composite. Meso-scale analysis of curved shallow-crossing linking 2.5D woven composite using the proposed model obtained the accurate tensile modulus. Full-scale analysis was implemented to simulate bending behavior of straight shallow-crossing linking 2.5D woven composite, and the simulation results agreed well with the experimental results. The above analysis could automatically complete modeling, analysis and post-processing in a relatively short time, reflecting the efficiency advantages of the method in this paper. [ABSTRACT FROM AUTHOR]

Information security holds paramount importance in the contemporary information society. Here, a novel cryptography method is proposed based on the multi‐wavelength complex‐amplitude metasurface, which can achieve a high security level by generating a frequency‐selective key as an additional layer of protection. Moreover, the quality of the decrypted holographic images can be significantly improved by employing the complex‐amplitude encoding method and the modified visual secret sharing scheme, which adopts a new superposition operator to prevent fidelity loss. As a proof‐of‐concept demonstration, a prototype metasurface sample is designed, fabricated, and characterized, where the measured results agree very well with the numerical ones and the design goals. The proposed method can reinforce security level and improve fidelity of the decrypted message, rendering it appealing for applications in communication and anti‐counterfeiting. [ABSTRACT FROM AUTHOR]