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A recent study from Zhejiang University School of Medicine highlights a case of eosinophilic duodenitis misdiagnosed as acute pancreatitis in a child. The patient, a 13-year-old girl, presented with symptoms of abdominal distension, vomiting, and epigastric pain, leading to a suspected diagnosis of acute pancreatitis. However, further investigation revealed eosinophilic duodenitis, a rare inflammatory disorder, which was successfully treated with oral prednisone tapering. This case underscores the importance of considering non-EoE EGIDs in children with peripheral blood eosinophilia and duodenal wall thickening. [Extracted from the article]