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Implementing Information and Communication Technologies (ICTs) in the healthcare sector faces several barriers, and the pace of adoption may vary depending on several factors, including individual attributes such as competence and experience, along with contextual factors such as size, type, and location of the organization. We conducted a global survey involving healthcare professionals (n =204) to understand the role of various determinants in adopting ICTs and their implications for organizational performance. Data was analyzed using Partial Least Squares Structural Equation Modelling (PLS-SEM) and multiple regression for micro-level constructs. Findings indicate that while individual attributes positively influence organizational performance, the direct impact of ICT adoption on performance is limited. While front-end technologies enhance performance, base technologies may occasionally hinder it. This stresses the necessity of thoroughly assessing specific technology applications to ensure they operate effectively. Furthermore, the relationships between competence and experience in ICT adoption were not statistically significant, indicating that individual attributes may have less influence on ICT adoption; this implies that technological advancements typically occur through management decisions in collaboration with the relevant IT department, emphasizing the importance of increased user participation and the process of adoption and effective use, which are distinct aspects while evaluating individual aspects. Future research should focus on detailed and specific applications of technology and nuanced, long-term performance outcomes.