1. Entamoeba invadens: influence of 60 Hz magnetic fields on growth and differentiation.
- Author
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Rodríguez-De la Fuente AO, Heredia-Rojas JA, Mata-Cárdenas BD, Vargas-Villarreal J, Rodríguez-Flores LE, Balderas-Candanosa I, and Alcocer-González JM
- Subjects
- Animals, Antiprotozoal Agents pharmacology, Dose-Response Relationship, Radiation, Entamoeba drug effects, Entamoeba physiology, Lethal Dose 50, Metronidazole pharmacology, Random Allocation, Electromagnetic Fields, Entamoeba growth & development, Entamoeba radiation effects
- Abstract
Exposure to extremely low-frequency (ELF) electromagnetic fields appears to result in a number of important biological changes. In the present study, we evaluated the effects of 60 Hz sinusoidal magnetic fields (MF) at magnetic flux densities of 1.0, 1.5 and 2.0 mT on growth and differentiation of the protozoan Entamoeba invadens. We demonstrated an inhibitory growth effect when trophozoite cultures were exposed to 1.5 and 2.0 mT. Furthermore, we found that there was not a synergistic effect in cultures co-exposed to MF and Metronidazole, a cytotoxic drug against amoebic cells. In addition, MF exposure inhibited the encystation process of E. invadens.
- Published
- 2008
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