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Abstract: Inspired by recent work of Cerulli, Feigin and Reineke on desingularizations of quiver Grassmannians of representations of Dynkin quivers, we obtain desingularizations in considerably more general situations and in particular for Grassmannians of modules over iterated tilted algebras of Dynkin type. Our desingularization map is constructed from Nakajima's desingularization map for graded quiver varieties. [Copyright &y& Elsevier]

Abstract: We prove that the frieze sequences of cluster variables associated with the vertices of an affine quiver satisfy linear recurrence relations. In particular, we obtain a proof of a recent conjecture by Assem–Reutenauer–Smith. [Copyright &y& Elsevier]

Abstract: We show that Derksen–Weyman–Zelevinsky''s mutations of quivers with potential yield equivalences of suitable 3-Calabi–Yau triangulated categories. Our approach is related to that of Iyama–Reiten and ‘Koszul dual’ to that of Kontsevich–Soibelman. It improves on previous work by Vitória. In Appendix A, the first-named author studies pseudo-compact derived categories of certain pseudo-compact dg algebras. [Copyright &y& Elsevier]

Abstract: By a theorem due to the first author, the bounded derived category of a finite dimensional algebra over a field embeds fully faithfully into the stable category over its repetitive algebra. This embedding is an equivalence if the algebra is of finite global dimension. The purpose of this paper is to investigate the relationship between the derived category and the stable category over the repetitive algebra from various points of view for algebras of infinite global dimension. The most satisfactory results are obtained for Gorenstein algebras, especially for selfinjective algebras. [Copyright &y& Elsevier]

Abstract: We prove that in a 2-Calabi–Yau triangulated category, each cluster tilting subcategory is Gorenstein with all its finitely generated projectives of injective dimension at most one. We show that the stable category of its Cohen–Macaulay modules is 3-Calabi–Yau. We deduce in particular that cluster-tilted algebras are Gorenstein of dimension at most one, and hereditary if they are of finite global dimension. Our results also apply to the stable (!) endomorphism rings of maximal rigid modules of [Christof Geiß, Bernard Leclerc, Jan Schröer, Rigid modules over preprojective algebras, arXiv: math.RT/0503324, Invent. Math., in press]. In addition, we prove a general result about relative 3-Calabi–Yau duality over non-stable endomorphism rings. This strengthens and generalizes the Ext-group symmetries obtained in [Christof Geiß, Bernard Leclerc, Jan Schröer, Rigid modules over preprojective algebras, arXiv: math.RT/0503324, Invent. Math., in press] for simple modules. Finally, we generalize the results on relative Calabi–Yau duality from 2-Calabi–Yau to d-Calabi–Yau categories. We show how to produce many examples of d-cluster tilted algebras. [Copyright &y& Elsevier]

For any finite dimensional algebra Λ given by a quiver with relations, we prove that its dg singularity category is quasi-equivalent to the perfect dg derived category of a dg Leavitt path algebra. The result might be viewed as a deformed version of the known description of the dg singularity category of a radical-square-zero algebra in terms of a Leavitt path algebra with trivial differential. The above result is achieved in two steps. We first introduce the singular Yoneda dg category of Λ, which is quasi-equivalent to the dg singularity category of Λ. The construction of this new dg category follows from a general operation for dg categories, namely an explicit dg localization inverting a natural transformation from the identity functor to a dg endofunctor. This localization turns out to be quasi-equivalent to a dg quotient category. Secondly, we prove that the endomorphism algebra of the quotient of Λ modulo its Jacobson radical in the singular Yoneda dg category is isomorphic to the dg Leavitt path algebra. The appendix is devoted to an alternative proof of the result using Koszul-Moore duality and derived localizations. [ABSTRACT FROM AUTHOR]

Abstract: In this article we study Cohen–Macaulay modules over one-dimensional hypersurface singularities and the relationship with the representation theory of associative algebras using methods of cluster tilting theory. We give a criterion for existence of cluster tilting objects and their complete description by homological methods, using higher almost split sequences and results from birational geometry. We obtain a large class of 2-CY tilted algebras which are finite-dimensional symmetric and satisfy . In particular, we compute 2-CY tilted algebras for simple and minimally elliptic curve singularities. [Copyright &y& Elsevier]

Neuronal injury in bacterial meningitis is caused by the interplay of host inflammatory responses and direct bacterial toxicity. We investigated the mechanisms by which pneumolysin, a cytosolic pneumococcal protein, induces damage to neurons. The toxicity after exposure of human SH-SY5Y neuroblastoma cells and hippocampal organotypic cultures to pneumolysin was time- and dose-dependent. Pneumolysin led to a strong calcium influx apparently mediated by pores on the cell membrane formed by the toxin itself and not by voltage-gated calcium channels. Buffering of intracellular calcium with BAPTA-AM [1, 2-bis (o-aminophenoxy) ethane N, N, N′, N′-tetraacetic acid tetra(acetomethoxyl) ester] improved survival of neuronal cells following challenge with pneumolysin. Western blotting revealed increased phosphorylation of p38 mitogen-activated protein kinase (p38 MAPK) as early as 30 min after challenge with pneumolysin. SB 203580, a potent and selective inhibitor of p38 MAPK, rescued human neuronal cells from pneumolysin-induced death. Inhibition of the mitochondrial permeability transition pore using bongkrekate and caspase inhibition also improved survival following challenge with the toxin. Modulation of cell death pathways activated by pneumolysin may influence the outcome of pneumococcal meningitis. [Copyright &y& Elsevier]