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[Display omitted] Electrical bioadhesive interfaces (EBIs) are standing out in various applications, including medical diagnostics, prosthetic devices, rehabilitation, and human–machine interactions. Nonetheless, crafting a reliable and advanced EBI with comprehensive properties spanning electrochemical, electrical, mechanical, and self-healing capabilities remains a formidable challenge. Herein, we develop a self-healing EBI by thoughtfully integrating conducting polymer nanofibers and a typical bioadhesive within a robust hydrogel matrix. The accomplished EBI demonstrates extraordinary adhesion (lap shear strength of 197 kPa), exceptional electrical conductivity (2.18 S m−1), and outstanding self-healing performance. Taking advantage of these attributes, we integrated the EBI into flexible skin electrodes for surface electromyography (sEMG) signal recording from forearm muscles. The engineered skin electrodes exhibit robust adhesion to the skin even when sweating, rapid self-healing from damage, and seamless real-time signal recording with a higher signal-to-noise ratio (39 dB). Our EBI, along with its skin electrodes, offers a promising platform for tissue-device integration, health monitoring, and an array of bioelectronic applications. [ABSTRACT FROM AUTHOR]

[Display omitted] • We develop a PEDOT-MeOH:PSS/PDA interface by a two-step electropolymerization method. • The prepared interface shows strong adhesion with 93% area retention after sonication for 20 min. • We further demonstrate the PEDOT-MeOH:PSS/PDA interface integrated on an ultrasmall Pt-Ir wire microelectrode with a diameter of only 10 μm. • The modified implantable neural microelectrodes display two orders of magnitude lower impedance than commercial products, and also superior long-term stability after 10,000,000 biphasic input pulse cycles. Conducting polymers are emerging as promising neural interfaces towards diverse applications such as deep brain stimulation due to their superior biocompatibility, electrical, and mechanical properties. However, existing conducting polymer-based neural interfaces still suffer from several challenges and limitations such as complex preparation procedures, weak interfacial adhesion, poor long-term fidelity and stability, and expensive microfabrication, significantly hindering their broad practical applications and marketization. Herein, we develop an adhesive and long-term stable conducting polymer neural interface by a simple two-step electropolymerization methodology, namely, the pre-polymerization of polydopamine (PDA) as an adhesive thin layer followed by electropolymerization of hydroxymethylated 3,4-ethylenedioxythiophene (EDOT-MeOH) with polystyrene sulfonate (PSS) to form stable interpenetrating PEDOT-MeOH:PSS/PDA networks. As-prepared PEDOT-MeOH:PSS/PDA interface exhibits remarkably improved interfacial adhesion against metallic electrodes, showing 93% area retention against vigorous sonication for 20 min, which is one of the best tenacious conducting polymer interfaces so far. Enabled by the simple methodology, we can facilely fabricate the PEDOT-MeOH:PSS/PDA interface onto ultrasmall Pt-Ir wire microelectrodes (diameter: 10 μm). The modified microelectrodes display two orders of magnitude lower impedance than commercial products, and also superior long-term stability to previous reports with high charge injection capacity retention up to 99.5% upon 10,000,000 biphasic input pulse cycles. With these findings, such a simple methodology, together with the fabricated high-performance and stable neural interface, can potentially provide a powerful tool for both advanced neuroscience researches and cutting-edge clinical applications like brain-controlled intelligence. [ABSTRACT FROM AUTHOR]

[Display omitted] Herein, a ternary-nanocomposite Pd-polypyrrole/nitrogen-doped graphene (Pd-PPy/NGE) has been prepared facilely by the one-pot method. In simple terms, PPy was in-situ polymerized on the surface of NGE with PdCl 4 2- as the oxidant, and simultaneously Pd nanopaticles were loaded on the surface of PPy or embedded in PPy particles. The obtained Pd-PPy/NGE nanocomposite exhibits promising electrocatalytic properties toward the oxidation reaction of alcohols in alkaline medium. Especially, the optimized Pd-PPy/NGE (1:50) catalyst possesses mass activity of 2176.7, 1192.7 and 498.9 mA mg Pd -1 toward ethylene glycol, methanol and ethanol electrooxidation, respectively, which are 4.3, 6.7 and 2.9 times of those for commercial Pd/C catalyst. Moreover, the Pd-PPy/NGE (1:50) also shows higher anti-poisoning ability and operating stability than the Pd/C catalyst. The promising electrocatalytic performance of the Pd-PPy/NGE (1:50) for alcohols oxidation can be ascribed to the well dispersion of Pd nanoparticles, the porous and stable three dimentional structure of the composite, and the synergistic effect between different components. The structural randomness of the conducting polymer and the potential synergistic effect between the metal nanoparticles and various supports would provide broad development space for these composites as electrocatalysts in direct alcohol fuel cell. [ABSTRACT FROM AUTHOR]