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FeSe microparticles coated by ultrathin nitrogen-doped carbon (FeSe@NC) have been synthesized through the dopamine coating of FeOOH precursor and the post-calcination treatment. The strong interfacial interaction between FeSe and NC guarantees FeSe@NC with fast electron/Na+ transport kinetics and outstanding structural stability. [Display omitted] • FeSe@NC exhibits preeminent performance as an anode for sodium-ion batteries. • Analyses of ex-situ XRD, ex-situ TEM and DFT calculations reveal that the electrochemical mechanism in FeSe. • Excellent performance is related to a reversible phase transformation from hexagonal to tetragonal. • NVPF@rGO//FeSe@NC full battery maintains a capacity of 241 mAh/g after 2000 cycles at 1 A/g. Transition metal selenides have gained enormous interest as anodes for sodium ion batteries (SIBs). Nonetheless, their large volume expansion causing poor rate and inferior cycle stability during Na+ insertion/extraction process hinders their further applications in SIBs. Herein, a confined-regulated interfacial engineering strategy towards the synthesis of FeSe microparticles coated by ultrathin nitrogen-doped carbon (NC) is demonstrated (FeSe@NC). The strong interfacial interaction between FeSe and NC endows FeSe@NC with fast electron/Na+ transport kinetics and outstanding structural stability, delivering unexceptionable rate capability (364 mAh/g at 10 A/g) and preeminent cycling durability (capacity retention of 100 % at 1 A/g over 1000 cycles). Furthermore, various ex situ characterization techniques and density functional theory (DFT) calculations have been applied to demonstrate the Na+ storage mechanism of FeSe@NC. The assembled Na 3 V 2 (PO 4) 2 F 3 @rGO//FeSe@NC full cell also displays a high capacity of 241 mAh/g at 1 A/g with the capacity retention of nearly 100 % over 2000 cycles, and delivers a supreme energy density of 135 Wh kg−1 and a topmost power density of 495 W kg−1, manifesting the latent applications of FeSe@NC in the fast charging SIBs. [ABSTRACT FROM AUTHOR]

Vitiligo is an autoimmune skin disease resulting from epidermal melanocyte destruction mediated by CD8+T cells that breach the self-tolerance. Regulatory T cells (Tregs) are critical for keeping the CD8+T cells in check, but the deficiency of Tregs leading to the immune disequilibrium in vitiligo remains undefined. In the present study, we used RNA-sequencing (RNA-seq) to acquire the transcriptome data of Tregs from vitiligo patients and healthy controls, respectively. Further flow cytometry analysis and immunofluorescence assays substantiated the phenotype of Th1-like Tregs in vitiligo. CD8+T cell-/vitiligo serum-Treg co-culture assays and chemotaxis assays were used to functionally examine this subset of Tregs. As a result, RNA-seq, flow cytometry, and immunofluorescence all indicated the transition of bona fide Treg to the Th1-like T-bet+IFN-γ+Treg in vitiligo patients. Besides, these Th1-like Tregs exhibited significantly dampened suppression on the proliferation and activation of CD8+T cells and a markedly higher tendency to be chemoattracted by CXCL10 and CXCL16. More interestingly, vitiligo serum could even elicit bona fide Tregs of healthy controls to adopt the Th1-like phenotype and manifest impaired suppression. To conclude, Tregs from vitiligo patients are functionally disturbed and the Th1-skewed inflammatory microenvironment in the serum of vitiligo patients is responsible for the generation of Th1-like Tregs. We provide a clinical exploitable strategy that in addition to simply replenishing the bona fide Treg or promoting the homing of Treg to the skin, the normalization of the Th1-skewed inflammatory environment in vitiligo patients and targeting the incompetent Th1-like Tregs might be critical in the future treatment of vitiligo. [Display omitted] • A part of Tregs in vitiligo patients adopts the Th1 phenotype, like expressing T-bet. • Th1-like Tregs deficiently inhibit the proliferation and activation of CD8+T cells. • Th1-like Tregs are more inclined to be chemoattracted by CXCL10 and CXCL16. • Vitiligo serum facilitates the conversion of normal Tregs to Th1-like Tregs. [ABSTRACT FROM AUTHOR]

BaLuF 5 :Ce,Tb,Eu(Sm) submicrospheres were synthesized via an ILs/ethylene glycol(EG) two-phase system. The crystalline phase, size, morphology, and luminescence properties were characterized using powder X-ray diffraction (XRD), field emission-scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), photoluminescence (PL) spectra. The results show that 1-methyl-3-octylimidazolium hexafluorophosphate ([Omim]PF 6 ) was used as fluoride source and capping agent to tune morphology and size of the crystals. The formation mechanism has been supposed. Under the excitation of ultraviolet, the BaLuF 5 :5%Ce 3+ ,5%Tb 3+ , BaLuF 5 :Eu 3+ , and BaLuF 5 :5%Ce 3+ ,5%Sm 3+ exhibit green and red emission, which was derived from Tb 3+ , Eu 3+ , and Sm 3+ emission. When codoping Ce 3+ , Tb 3+ , Sm 3+ or Eu 3+ together, multi-color emission can be realized. Furthermore, this synthetic route may have potential applications for fabricating other lanthanide fluorides. [ABSTRACT FROM AUTHOR]