1. Heterostructures of mesoporous TiO 2 and SnO 2 nanocatalyst for improved electrochemical oxidation ability of vitamin B6 in pharmaceutical tablets
- Author
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Rabah Boukherroub, Saravanan Rajendran, Miguel A. Gracia-Pinilla, Devaraj Manoj, Francisco Gracia, E. Sundaravadivel, Jiaqian Qin, Vinod Kumar Gupta, Mehmet Lütfi Yola, Necip Atar, Mühendislik ve Doğa Bilimleri Fakültesi -- Biyomedikal Mühendisliği Bölümü, Yola, Mehmet Lütfi, Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 (IEMN), Centrale Lille-Institut supérieur de l'électronique et du numérique (ISEN)-Université de Valenciennes et du Hainaut-Cambrésis (UVHC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF), NanoBioInterfaces - IEMN (NBI - IEMN), Centrale Lille-Institut supérieur de l'électronique et du numérique (ISEN)-Université de Valenciennes et du Hainaut-Cambrésis (UVHC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-Centrale Lille-Institut supérieur de l'électronique et du numérique (ISEN)-Université de Valenciennes et du Hainaut-Cambrésis (UVHC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF), Indian Institute of Technology Roorkee (IIT Roorkee), İskenderun Teknik Üniversitesi, Gupta, Vinod Kumar -- 0000-0003-2809-2966, Atar, Necip -- 0000-0001-8779-1412, and Qin, Jiaqian -- 0000-0002-9166-3533
- Subjects
titanium dioxide nanoparticle ,Tin oxide nanoparticle ,Electrode ,Limit of detection ,Surface area ,High resolution transmission electron microscopy ,02 engineering and technology ,Ionic liquid ,Electrochemistry ,01 natural sciences ,Nanocomposites ,X ray fluorescence ,Nanoparticle ,Chemical structure ,electrochemical analysis ,ComputingMilieux_MISCELLANEOUS ,Titanium ,Titanium dioxide nanoparticle ,Differential pulse voltammetry ,Surface property ,Tin oxides ,tin oxide nanoparticle ,Reproducibility ,3. Good health ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Cyclic potentiometry ,Electrochemical oxidation ,priority journal ,Gas ,Glass membrane electrodes ,0210 nano-technology ,Sensitivity analysis ,Tablets ,oxidation ,Composite electrode ,Titanium dioxide (TiO2) ,chemistry ,Biosynthesis ,Sensitivity and Specificity ,Nanofabrication ,Article ,Tin oxide (SnO 2 ) cocatalyst ,Biomaterials ,[CHIM.ANAL]Chemical Sciences/Analytical chemistry ,Stannic oxide ,Pharmaceutical quality control ,Voltammetric determination ,reproducibility ,Sensor ,Detection limit ,nanocatalyst ,titanium dioxide ,Titanium dioxides (TiO2) ,Tin Compounds ,surface area ,Titanium oxides ,Electrochemical Techniques ,Vitamin B 6 ,Mesoporous materials ,0104 chemical sciences ,Electrochemical gas sensor ,tin derivative ,Tin dioxide ,ComputingMethodologies_PATTERNRECOGNITION ,Chemical engineering ,Vitamin B6 ,Nanocatalyst ,chemical structure ,Titanium dioxide ,Voltammetry ,Mesoporous material ,Oxidation reduction reaction ,Tablet ,oxidation reduction reaction ,Electrochemical platforms ,Unclassified drug ,high resolution transmission electron microscopy ,Coenzymes ,Impedance spectroscopy ,Vitamins | Voltammetry | Water-soluble vitamins ,Carbon nanotube ,Nanomaterials ,Degradation ,Colloid and Surface Chemistry ,sensitivity analysis ,Limit of Detection ,stannic oxide ,Tin derivative ,Priority journal ,X ray photoemission spectroscopy ,impedance spectroscopy ,Nanocomposite ,nanocomposite ,Enhancement ,nanoparticle ,Pyridoxine ,Tin oxide (SnO2) cocatalyst ,021001 nanoscience & nanotechnology ,unclassified drug ,ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS ,Chemistry ,Sensitivity and specificity ,InformationSystems_MISCELLANEOUS ,Titanium dioxide (TiO 2 ) ,Porosity ,Oxidation-Reduction ,Materials science ,surface property ,X ray diffraction ,Electrochemical analysis ,cyclic potentiometry ,Chemical detection ,Mesoporous ,Electrochemical surface area ,010402 general chemistry ,Catalysis ,Physical ,[CHIM]Chemical Sciences ,Electrochemical sensors ,Electrodes ,pyridoxine ,tablet ,Cocatalyst ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,Pyridoxine vitamin-b-6 ,electrode ,Electrochemical sensor ,nanofabrication ,Vitamin B-6 ,TiO2 nanoparticles ,Nanocatalysts - Abstract
WOS: 000461536400006, 30721835, The detection of water soluble vitamins using electrochemical method is widely established in pharmaceutical quality control laboratories, and especially the recent advances in hybrid heterostrucure nanomaterials has devoted to enhance the significant analytical parameters like sensitivity, selectivity and fast response time. Herein, we report the synthesis of a hybrid heterostructure comprising SnO2 nanopartides supported mesoporous TiO2, and the obtained nanocomposite were fabricated over glassy carbon electrode (GCE) for the electrochemical oxidation of vitamin B-6 in pharmaceutical tablets. The designed SnO2-TiO2/GC modified electrode exhibits well-defined oxidation peak with lowering over-potential and larger signal response compared to the pristine counterparts, and it is mainly due to the formation of abundant active surface layer offered by SnO2 cocatalyst, and thus significantly enhances the electrochemical surface area. Differential pulse voltammetry (DPV) measurements revealed a sharp increase in the anodic peak current upon addition of increasing concentration of vitamin B-6. The analytical performance of the modified electrode displayed a wide linear range (0.1-31.4 mu M), high selectivity, and excellent sensitivity (759.73 mu A mM(-1) cm(-2)) with low detection limit (35 nM). Thus, the resultant mesoporous hybrid nanocatalyst provides an efficient electrochemical platform for determination of various potential analytes. (C) 2019 Elsevier Inc. All rights reserved., CONICYT, Government of Chile [CONICYT/FONDAP/15110019]; FONDECYT Government of Chile [11170414], The authors (S.R., F.G.) acknowledge the support of CONICYT, Government of Chile through the project CONICYT/FONDAP/15110019. The author (S.R) acknowledge FONDECYT Government of Chile (Project No.: 11170414), for the support to carry out this project.
- Published
- 2019