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Increase in resistance of antibiotic against P. aeruginosa, the antibiotic treatment therapy fail to exterminate the infection. The approach of new strategy is must to deal with multidrug resistant P. aeruginosa. In the present study total 300 isolates from different clinical samples (Urine, Blood, Sputum, and Pus) were studied for isolation, identification and analysis of resistance pattern against 22 antibiotics. Total 5 most resistant isolates (U004, P017, P078, U105, and U237) were screened to search for synergistic approach of Coriandrum sativum extract prepared by both Soxhlet method and Maceration process in different solvents; petroleum ether, chloroform, acetone, methanol and water. Encouraging results were obtained where HDME extract could synergise the activity of total 8 antibiotics that are; MZ, CPZ, CTX, PB, LE, DOR, AZ and CAZ. Thus the present study provides and landmark approach to deal with multidrug resistant P. aeruginosa by synergistic action of antibiotic and Coriandrum sativum extract.

A reporting of an abnormality in the beak in a male Japanese quail, Coturnixcoturnix japonica, has been discussed in this paper. During the behavioral study of Japanese quails, a male differed markedly from the others due to its comparatively longer beak. The maxilla was abnormally elongated and curved over the mandible, which made it difficult to feed and drink.Beak deformities has been previously reported in the Antarctic Cormorant,Phalacrocoraxbransfieldensischick; White winged Becard,Pachyramphuspolychopterus; Passerines (Craves); Brown headed Cowbird; Black Wheatears, Oenantheleucura; Southern Giant Petrel, Macronectesgiganteus chick. But no such record of beak deformity in japanese quail has been studied. The reason behind this anomaly can be a subject of research.

Masala lake is situated 6 Km. away from Chandrapur. The present study has been made to investigate the physico-chemical parameters of the lake. The present study was carried out from the month of Aug. 2006 to Jan 2007. Samples were collected on monthly basis from three sampling stations S,,S, and S,. The physico­ chemical parameters like temp., pH, conductivity, DO, COD, BOD, free CO,, chloride, total hardness, Ca hardness, Mg hardness, phosphate, sulphate, nitrate, nitrites, carbonates & bicarbonates were analyzed during the course of study. The study revealed that as compared to site S, and S,, site S, showed higher concentration of sulphate, phosphate and bicarbonates during month of Nov and Dec 2006 and were recorded low during the month of Aug and Sept 2006 may be due to dilution, site S, shows more TDS value because of domestic activities. In all there is definite impact on the water quality due to domestic and agricultural activities.