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Your search keyword '"Markin VA"' showing total 6 results
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6 results on '"Markin VA"'

1. [Histotopography of changes in the enzyme activity of rat brain exposed to fluorophenazine].

Author

Liubimov BI, Markin VA, and Mitrofanov VS

Subjects
Animals, Brain drug effects, Male, Rats, Brain enzymology, Fluphenazine pharmacology, Isocitrate Dehydrogenase metabolism, NADH, NADPH Oxidoreductases metabolism, Succinate Dehydrogenase metabolism
Abstract

The influence of fluorophenazine on succinic-, citric acid-, NAD-H2-and NADP-H2-dehydrogenases in different structures of rat brain was investigated by histochemical methods. Three hours after a single subcutaneous injection of fluorophenazine (1 and 5 mg/kg) the enzymatic activity was the greatest in the limbic and the frontal regions of the cortex. The inhibitory effects of fluorophenazine in these structures were greater than those of the neuroleptics trifluoroperazine, chlorpromazine.

Published
1975

2. [Dynamics of changes in cerebral glucose-6-phosphate dehydrogenase activity under the influence of triftazin and fluoracizin].

Author

Markin VA and Mitrofanov VS

Subjects
Amygdala enzymology, Animals, Corpus Striatum enzymology, Depression, Chemical, Diethylamines pharmacology, Frontal Lobe enzymology, Hippocampus enzymology, Histocytochemistry, Hydrocarbons, Fluorinated pharmacology, Hypothalamus enzymology, Limbic System enzymology, Male, Mesencephalon enzymology, Parietal Lobe enzymology, Rats, Reticular Formation enzymology, Septum Pellucidum enzymology, Stimulation, Chemical, Superior Colliculi enzymology, Temporal Lobe enzymology, Thalamic Nuclei enzymology, Antidepressive Agents therapeutic use, Brain enzymology, Glucosephosphate Dehydrogenase metabolism, Phenothiazines pharmacology, Trifluoperazine pharmacology
Published
1974

3. [Possibility of the pharmacologic treatment of post-ischemic myocardial damage].

Author

Rozonov IuB, Morozova TV, Markin VA, and Pokazeeva ZT

Subjects
Angina Pectoris etiology, Angina Pectoris pathology, Animals, Coronary Disease complications, Coronary Disease pathology, Necrosis, Rabbits, Angina Pectoris prevention & control, Coronary Disease drug therapy, Moricizine analogs & derivatives, Myocardium pathology, Nonachlazine therapeutic use, Phenothiazines therapeutic use
Abstract

The influence of ethacizin and nonachlazin on the size of myocardial necrosis, caused by 1.5-hour partial occlusion of the coronary artery was studied in conscious rabbits. The drugs were administered for 3 days, after the blood supply in the ischemic zones had been recovered. Ethacizin had a more pronounced effect, as compared to nonachlazin. The data obtained suggest that in the case of isochemic heart disease pharmacotherapy can be used not only for the prevention and arrest of anginal attacks, but also for the treatment of postischemic cardiac lesions.

Published
1986

5. [Selective effect of triftazin on various sections of the rat brain reticular formation].

Author

Markin VA and Anefolov VA

Subjects
Animals, Cell Nucleus drug effects, Endoplasmic Reticulum drug effects, Golgi Apparatus drug effects, Lysosomes drug effects, Male, Medulla Oblongata cytology, Medulla Oblongata enzymology, Microscopy, Electron, Mitochondria drug effects, Oxidoreductases metabolism, Rats, Reticular Formation cytology, Reticular Formation enzymology, Medulla Oblongata drug effects, Reticular Formation drug effects, Trifluoperazine pharmacology
Published
1972

6. [Selective action of a new antidepressive agent fluoroacizine on the activity of pyridine dehydrogenases in the rat brain].

Author

Markin VA and Mitrofanov VS

Subjects
Amygdala enzymology, Animals, Caudate Nucleus enzymology, Cerebellar Cortex enzymology, Cerebral Cortex enzymology, Geniculate Bodies enzymology, Globus Pallidus enzymology, Glutamate Dehydrogenase metabolism, Glycerolphosphate Dehydrogenase metabolism, Hippocampus enzymology, Hypothalamus enzymology, Isocitrate Dehydrogenase metabolism, L-Lactate Dehydrogenase metabolism, Limbic System enzymology, Malate Dehydrogenase metabolism, Male, Medulla Oblongata enzymology, Parietal Lobe enzymology, Rats, Red Nucleus enzymology, Reticular Formation enzymology, Thalamic Nuclei enzymology, Thalamus enzymology, Antidepressive Agents pharmacology, Brain enzymology, Oxidoreductases metabolism, Phenothiazines pharmacology
Published
1971

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