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7 results on '"Simanina EV"'

1. [The blood-stimulating effect of granulocyte colony-stimulating factor during cytostatic exposure].

Author

Gol'dberg ED, Dygaĭ AM, Zdanov VV, Krivopalova GN, Masycheva VI, Pustoshilova NM, Pushkareva NS, Simanina EV, and Sinichkina SA

Subjects
Animals, Cells, Cultured, Colony-Forming Units Assay, Granulocytes cytology, Granulocytes drug effects, Humans, Male, Mice, Mice, Inbred CBA, Recombinant Proteins, Antineoplastic Agents toxicity, Cyclophosphamide toxicity, Granulocyte Colony-Stimulating Factor pharmacology, Hematopoiesis drug effects
Published
1999

2. [Role of mast cells in regulation of erythropoiesis during inflammation].

Author

Klimenko NA, Dygaí AM, Gumilevskií BI, Simanina EV, Sherstoboev EI, and Gol'dberg ED

Subjects
Animals, Bone Marrow pathology, Cell Division, Disease Models, Animal, Hematopoietic Stem Cells pathology, Male, Mice, Mice, Inbred CBA, Peritonitis blood, Erythropoiesis physiology, Mast Cells physiology
Published
1997

3. [Reaction of eritron and its mechanisms in inflammation].

Author

Gol'dberg ED, Dygaĭ AM, Klimenko NA, Gumilevskiĭ BIu, Simanina EV, and Sherstobaev EIu

Subjects
Animals, Male, Mice, Mice, Inbred CBA, Peritonitis microbiology, Erythroid Precursor Cells physiology, Escherichia coli Infections blood, Inflammation Mediators physiology, Peritonitis blood
Published
1995

4. [Mechanisms of the stimulating effect of d-glucuronic acid on the processes of bone marrow granulomonocytopoiesis in cytostatic myelodepression].

Author

Gol'dberg ED, Dygaĭ AM, Karpova GV, Simanina EV, Khlusov IA, Shakhov VP, and Agafonov VI

Subjects
Animals, Bone Marrow Cells, Cell Differentiation drug effects, Cell Division drug effects, Cyclophosphamide, Disease Models, Animal, Glucuronic Acid, Hematopoietic Stem Cells drug effects, Interleukin-1 biosynthesis, Mice, Mice, Inbred CBA, Stereoisomerism, Bone Marrow drug effects, Glucuronates pharmacology, Granulocytes drug effects, Hematopoiesis drug effects, Monocytes drug effects
Abstract

The mechanisms of regulating influence of D-glucuronic acid on granulomonocytopoiesis++ have been studied by using the model of cyclophosphamide-induced myelodepression. Increase of colony-stimulating and interleukin-1 activities production by hemopoiesis inducing microenvironment cells, the stimulation of hemopoietic islets and the different granulomonocytopoiesis precursor cells forming have been shown to be the base of activating action of D-glucuronic acid on bone marrow granulomonocytopoiesis recovery.

Published
1993

5. [Role of mast cells in reactions of the blood system in inflammation].

Author

Klimenko NA, Dygaĭ AM, Abramova EV, Simanina EV, Gumilevskiĭ BIu, Boldyshev DA, and Gol'dberg ED

Subjects
Acute Disease, Animals, Bone Marrow Cells, Hematopoiesis, Inflammation blood, Leukocytes physiology, Male, Mice, Mice, Inbred CBA, Neutrophils physiology, Peritonitis physiopathology, Inflammation physiopathology, Mast Cells physiology
Abstract

On the model of the acute infectious peritonitis in mice it is shown that the previously osmotic disruption of the peritoneal mast cell population remarkably affects the inflammatory focus, blood and bone-marrow leukocytic reactions. The initial neutrophil accumulation increase and the earlier and more intensive leukocytosis and activation of granulo-monocytopoiesis are established. At the same time the kinetics of monocytes in inflammatory focus is expressed weaker and testifies to the prolongation of the inflammatory response. Thus, in the natural inflammatory conditions mast cells of the inflammatory focus directly or indirectly modulate leukocytes and hematopoiesis.

Published
1991

6. [Modulating effect of enkephalins on hemopoieis under stress].

Author

Gol'dberg ED, Zakharova OIu, Dygaĭ AM, Simanina EV, and Agafonov VI

Subjects
Animals, Bone Marrow drug effects, Male, Mice, Restraint, Physical, Time Factors, Enkephalin, Leucine pharmacology, Enkephalin, Methionine pharmacology, Hematopoiesis drug effects, Stress, Psychological blood
Abstract

The influence of enkephalins on the medullary hemopoiesis has been studied during stress reaction in noninbred mice. It was shown that leu-enkephalin administration suppressed, while met-enkephalin injection stimulated granulocyto- and erythropoiesis during immobilization stress.

Published
1987

7. [Role of the thymus in regulating bone marrow hematopoiesis in the stress reaction].

Author

Dygaĭ AM, Kirienkova EV, Mikhlenko AV, Bulatova TA, and Simanina EV

Subjects
Animals, Cell Count, Mice, Mice, Inbred C57BL, Mice, Inbred CBA, Restraint, Physical, Thymectomy, Time Factors, Bone Marrow Cells, Hematopoiesis, Stress, Psychological physiopathology, Thymus Gland physiology
Abstract

The role of thymus in the regulation of erythropoiesis during stress has been studied in experiments on immobilized mice. The development of pronounced leukopenia due to stimulation of erythro- and granulocytopoiesis was demonstrated. Thymectomy, performed a month before immobilization, abolished the phenomenon of erythropoietic cellularity, indicating an important role of thymus in the regulation of myelopoiesis during stress.

Published
1986

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