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Your search keyword '"Zhukova Os"' showing total 4 results
Start Over Author "Zhukova Os" Publisher administrativnoia zdaniia minzdrava sssr
4 results on '"Zhukova Os"'

1. [Effect of glutamin(asparagin)ase preparations from microorganisms on DNA synthesis in tumor cells].

Author

Pekhov AA, Zhukova OS, Ivanova TP, Zanin VA, and Berezov TT

Subjects
Cell Line, Dose-Response Relationship, Drug, Humans, Amidohydrolases pharmacology, DNA, Neoplasm biosynthesis, Pseudomonas enzymology
Abstract

The effect of glutamin (asparagin)ase from Pseudomonas fluorescens and Pseudomonas boreopolis 526 on DNA synthesis by tumor cells, lines CaOv and L8, has been studied. The L8 cells have been demonstrated highly sensitive to the enzyme.

Published
1983

2. [Cytostatic effect of L-lysine-alpha-oxidase from Trichoderma harzianum Rifai and Trichoderma viride].

Author

Khaduev SKh, Zhukova OS, Dobrynin IaV, Soda K, and Berezov TT

Subjects
Cell Line, DNA, Neoplasm biosynthesis, DNA, Neoplasm drug effects, Depression, Chemical, Humans, Neoplasm Proteins biosynthesis, RNA, Neoplasm biosynthesis, RNA, Neoplasm drug effects, Amino Acid Oxidoreductases pharmacology, Antineoplastic Agents, Mitosporic Fungi enzymology, Neoplasms metabolism, Trichoderma enzymology
Abstract

L-lysine-alpha-oxidase, a new fungal enzyme catalyzing oxidative L-lysine deamination, was shown to have an inhibitory effect on the in vitro synthesis of DNA, RNA and proteins in human carcinoma ovarian (CaOv) cells.

Published
1987

3. [Comparative study of the effect of L-lysine-L-oxidase from Trichoderma harzianum Rifai and Trichoderma viride on nucleic acid synthesis in human tumor cells in vitro].

Author

Khaduev SKh, Zhukova OS, Dobrynin IaV, Soda K, and Berezov TT

Subjects
Cells, Cultured, Depression, Chemical, Female, Humans, Neoplasm Proteins biosynthesis, Ovarian Neoplasms metabolism, Amino Acid Oxidoreductases pharmacology, DNA, Neoplasm biosynthesis, Mitosporic Fungi enzymology, RNA, Neoplasm biosynthesis, Trichoderma enzymology
Abstract

L-lysine-alpha-oxidase, a new fungal enzyme catalyzing oxidative deamination of L-lysine, exerts an inhibitory effect on DNA, RNA and protein synthesis in human cells of carcinoma ovarius (CaOv) in vitro.

Published
1986

4. [Cytotoxic effect of methionine-gamma-lyase on neoplastic cells in culture].

Author

Pekhov AA, Zhukova OS, Ivanova TP, Zanin VA, and Dobrynin IaV

Subjects
Animals, Cells, Cultured drug effects, Female, L Cells drug effects, Mice, Ovarian Neoplasms, Pseudomonas enzymology, Antineoplastic Agents pharmacology, Carbon-Sulfur Lyases pharmacology, DNA, Neoplasm biosynthesis, Lyases pharmacology
Abstract

The influence of methionine-gamma-lyase from Pseudomonas putida on DNA synthesis by CaOv and L-8 cell lines has been studied. The agent has been demonstrated to inhibit the incorporation of 3H-thymidine into L-8 cell line and to have no effect on CaOv cells.

Published
1983

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