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Although malignant lymphomais split in over 60 distinct entities , four of them, diffuse large Bcelllym phoma , follicular-, Hodgkin's - and mantle cell lymphoma constitute more than half of a ll new cases. A recent major revision of the Ann Arbor staging system restricts the suffix “A" and “ B" just to Hodgkin 'slymphoma . Bone marrow exams are abandonned in Hodgkin 's and restricted in DLBCL. PET exams at different time points are crucial. PET guided therapy will lead to a reduction of the use of chemo - and radi tion therapy. Many new targeted drugs have been introduced . Their therapeutic index is impressive as is their price tag. The radiation and chemo therapy free treatment of malignant lymphoma is with in reach. [ABSTRACT FROM AUTHOR]