Search

Ventricular arrhythmias (VAS), Including ventricular tachycardia (VT), ventricular fibrillation (VF) and Brady-arrhythmias, are life-threatening complications of acute myocardial infarction (MI). Objective: To study the incidence of ventricular arrhythmias, brady-arrhythmias and Sudden Cardiac Death (SCD) in Sudanese patients with acute MI. Methodology: This is a prospective cross sectional, hospital based study, conducted at Elshaab Teaching Hospital Khartoum Sudan. One Hundred Sudanese patients with acute MI were enrolled in the study in the period between August 2006 and December 2006. A questionnaire was constructed in sections to address the different aspect of the study group. ECG Monitor was used to confirm the complication in every patient. Result:Of the study group forty seven (47%) patients were 55-65 years old, twenty eight (28%) were more than 65 years old and twenty five (25%) were less than 55 years old. Sixty nine (69%) were males. Twenty patients (20%) developed complications [ventricular arrhythmias (VAS), Brady-arrhythmias and SCD]. Conclusion: The incidence of ventricular arrhythmias, brady-arrhythmias and sudden cardiac death following acute myocardial infarction were significantly high in Sudanese patients. The increased incidence is even in all age groups. DM, smoking and past history of IHD are the commonest associated risk factors. Thrombolysis is under used and had no significant impact. Keywords : thrombolysis, fibrillation, ischemia, Dyslipidaemia Sudan Journal of Medical Science Vol. 3 (4) 2008: pp. 325-332

Coronary artery disease is one of the l wide. lipoprotein(a) [Lp (a)] is a cholesterol rich plasma lipoprotein Its structure and composition closely resembles low density lipoproteins (LDL). Elevated Lp (a) is the most common familial lipoprotein disorder in patients with premature Coronary Artery Disease (CAD). Objective: To study the pattern of plasma LP(a) levels in Sudanese patients who presented with coronary artery disease [CAD]. Material and Methods: This is a case control study. 30 patients randomly se admitted to the coronary care unit [C.C.U] in Elshaab Teaching Hospital with acute coronary syndrome in the period from April 2004 to July 2005 while 30 patients with non ischaemic cardiac problems admitted to the same ho randomly selected as a matched control group. Serum LP(a), cholesterol and low C) concentrations were determined using the conventional enzymatic colorimetric methods. Results: LP(a), cholesterol and LDL lev respectively]. Lp(a) is also high in patients blew 60years of age. High LP(a) correlates with high cholesterol, LDL and other risk factors. The role of Lp(a) as an independent 15 patients with no other risk factors had high LP(a) level. Conclusion: This study demonstrated significant Lp(a) level in patients with other risk factors of CAD [including cholesterol and LDL].