1. Nonlinear Synchronization Analysis of Spatiotemporal Heart Data
- Author
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Jennifer Simonotto, Mark L. Spano, Michael D. Furman, William L. Ditto, Katherine M. Kavanagh, and Gang Liu
- Subjects
Pixel ,Defibrillation ,Computer science ,medicine.medical_treatment ,Acoustics ,Frame (networking) ,Video camera ,Reentry ,medicine.disease ,Synchronization ,law.invention ,Nonlinear system ,law ,Ventricular fibrillation ,medicine ,Electronic engineering - Abstract
A high‐speed video camera and voltage‐sensitive dyes were used to acquire high resolution (80×80 pixels) and high‐speed (500 μs/frame) optical signals of ventricular fibrillation in a Langendorff‐perfused porcine heart. The resulting spatiotemporal dynamics were recorded before and after the application of a defibrillation shock in order to study the mechanism of defibrillation failure. We calculate nonlinear synchronization index measures to qualify the evolution of different types of activity on the heart surface (focal, reentry). We observe changes with time in the spatial distribution of the first Fourier mode, showing that two main types of activity compete on the heart surface during a failed defibrillation.
- Published
- 2003
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