1. Surface anchored metal-organic frameworks as stimulus responsive antifouling coatings.
- Author
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Sancet MP, Hanke M, Wang Z, Bauer S, Azucena C, Arslan HK, Heinle M, Gliemann H, Wöll C, and Rosenhahn A
- Subjects
- Biofouling prevention & control, Surface Properties, Metals chemistry
- Abstract
Surface-anchored, crystalline and oriented metal organic frameworks (SURMOFs) have huge potential for biological applications due to their well-defined and highly-porous structure. In this work we describe a MOF-based, fully autonomous system, which combines sensing, a specific response, and the release of an antimicrobial agent. The Cu-containing SURMOF, Cu-SURMOF 2, is stable in artificial seawater and shows stimulus-responsive anti-fouling properties against marine bacteria. When Cobetia marina adheres on the SURMOF, the framework's response is lethal to the adhering microorganism. A thorough analysis reveals that this response is induced by agents secreted from the microbes after adhesion to the substrate, and includes a release of Cu ions resulting from a degradation of the SURMOF. The stimulus-responsive antifouling effect of Cu-SURMOF 2 demonstrates the first application of Cu-SURMOF 2 as autonomous system with great potential for further microbiological and cell culture applications.
- Published
- 2013
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