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Objective: Evaluation of fetal and maternal outcomes in pregnancy with leiomyoma uteri. Methods: Total 50 pregnant women with uterine myoma attending the department of Obstetrics and Gynecology of IPGME&R, Kolkata were followed during the antenatal, intranatal and postnatal period. Total 200 women of normal uncomplicated pregnancy were recruited as control and matched for age and parity. Results: The women were having 10% submucous, 74% intramural and 16% subserous type of uterine myoma. Highest incidence was in more than 30 yrs age group. Spontaneous miscarriage in 16%, malpresentation in 14%, fetal growth restriction (FGR) in 14%, intra uterine fetal demise (IUFD) in 8% and placental abruption in 8% cases were noted. During intranatal period preterm labour in 18%, prolonged labour in 22%, fetal distress in 22%, retained placenta in 6% and preterm premature rupture of membranes (PPROM) or premature rupture of membranes (PROM) in 16% cases were also seen. Postpartum hemorrhage (PPH) in 22% and subinvolution in 14% cases were found. APGAR score was less than seven in 18% babies and 46% babies weighed low birth weight. Conclusion: Pregnancies complicated with uterine myoma adversely affect fetal and maternal outcomes.

Heridetary motor and sensory neuropathy (HMSN TYPE-2) reflects reduction in the number of primary motor and sensory neurons. The occurrence of this disease is rare in pregnancy but may be exaggerated in pregnancy leading to preeclampsia / eclampsia. Here is a 28 years old 2nd gravidae with twin pregnancy at 31 weeks hospitalized with HMSN TYPE-2 disease and was managed successfully with good feto maternal outcome