Search

Your search keyword '"Lasarte JJ"' showing total 1 results
Start Over Author "Lasarte JJ" Publisher almquist and wiksell

Refine your results

1 results on '"Lasarte JJ"'

1. Effect of recombinant human growth hormone therapy on bone and clinical parameters in girls with Turner's syndrome. The Spanish Collaborative Group.

Author

Ferrández A, Mayayo E, Arnal JM, García C, Buñuel C, Lasarte JJ, Anton R, and Puyuelo P

Subjects
Adolescent, Child, Child, Preschool, Drug Therapy, Combination, Ethinyl Estradiol therapeutic use, Female, Humans, Oxandrolone therapeutic use, Recombinant Proteins, Skinfold Thickness, Bone Development drug effects, Growth Disorders drug therapy, Growth Hormone therapeutic use, Turner Syndrome complications
Abstract

Forty-eight girls with Turner's syndrome were assigned to one of three treatments; recombinant human growth hormone (rhGH) alone, rhGH plus oxandrolone, and rhGH plus ethinyloestradiol. Treatment with rhGH alone or in combination with oxandrolone induced catch-up growth. Older girls treated with rhGH plus ethinyloestradiol showed less marked improvement. The gain in height was associated with a gain in bone diameter and cortical thickness (reflecting increased bone mass). There was a rapid loss of subcutaneous fat. These effects of growth hormone are similar to those observed in patients with growth hormone deficiency.

Published
1989
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results