1. Reducing Antibiotic Prescribing in Primary Care for Respiratory Illness
- Author
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Rita Mangione-Smith, Alexander G. Fiks, Louise Warren, Jennifer Steffes, Benjamin Hedrick, Laura P. Shone, Jeffrey D. Robinson, Jeffrey S. Gerber, Margaret Wright, James W. Stout, Robert W. Grundmeier, Matthew P. Kronman, Chuan Zhou, Madeleine U. Shalowitz, and Dennis Burges
- Subjects
Male ,medicine.medical_specialty ,medicine.drug_class ,Antibiotics ,Inappropriate Prescribing ,Education, Distance ,03 medical and health sciences ,0302 clinical medicine ,Streptococcal Infections ,030225 pediatrics ,Internal medicine ,Outpatients ,Confidence Intervals ,Odds Ratio ,medicine ,Humans ,Pediatricians ,Program Development ,Sinusitis ,Medical prescription ,Bronchitis ,Child ,Respiratory Tract Infections ,Chicago ,Primary Health Care ,Respiratory tract infections ,business.industry ,Communication ,Infant ,Respiratory infection ,Pharyngitis ,medicine.disease ,Quality Improvement ,Anti-Bacterial Agents ,Intention to Treat Analysis ,Pediatric Nursing ,Clinical trial ,Otitis Media ,Logistic Models ,Child, Preschool ,Acute Disease ,Pediatrics, Perinatology and Child Health ,Female ,medicine.symptom ,business - Abstract
BACKGROUND: One-third of outpatient antibiotic prescriptions for pediatric acute respiratory tract infections (ARTIs) are inappropriate. We evaluated a distance learning program’s effectiveness for reducing outpatient antibiotic prescribing for ARTI visits. METHODS: In this stepped-wedge clinical trial run from November 2015 to June 2018, we randomly assigned 19 pediatric practices belonging to the Pediatric Research in Office Settings Network or the NorthShore University HealthSystem to 4 wedges. Visits for acute otitis media, bronchitis, pharyngitis, sinusitis, and upper respiratory infection for children 6 months to RESULTS: Among 72 723 ARTI visits by 29 762 patients, intention-to-treat analyses revealed a 7% decrease in the probability of antibiotic prescribing for ARTI overall between the baseline and postintervention periods (aRR 0.93; 95% confidence interval [CI], 0.90–0.96). Second-line antibiotic prescribing decreased for streptococcal pharyngitis (aRR 0.66; 95% CI, 0.50–0.87) and sinusitis (aRR 0.59; 95% CI, 0.44–0.77) but not for acute otitis media (aRR 0.93; 95% CI, 0.83–1.03). Any antibiotic prescribing decreased for viral ARTIs (aRR 0.60; 95% CI, 0.51–0.70). CONCLUSIONS: This program reduced antibiotic prescribing during outpatient ARTI visits; broader dissemination may be beneficial.
- Published
- 2020
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