1. Severe Varicella Caused by Varicella-Vaccine Strain in a Child With Significant T-Cell Dysfunction
- Author
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Anne A. Gershon, William Borkowsky, Mary Wu Chang, Philip LaRussa, Patrick Jean-Philippe, Sharon Steinberg, and Abigail Freedman
- Subjects
Pediatrics ,medicine.medical_specialty ,Varicella vaccine ,T-Lymphocytes ,media_common.quotation_subject ,Chickenpox Vaccine ,T-cell dysfunction ,Chickenpox ,medicine ,Humans ,Girl ,Immunodeficiency ,media_common ,business.industry ,Immunologic Deficiency Syndromes ,Infant ,medicine.disease ,Rash ,Pneumonia ,Pediatrics, Perinatology and Child Health ,Immunology ,Female ,medicine.symptom ,business - Abstract
In March 1995, the US Food and Drug Administration approved a live attenuated varicella vaccine for use in healthy children 12 months to 12 years old. We report here an 18-month-old girl with cell-mediated immunodeficiency who developed a severe vaccine-associated rash and clinical evidence of vaccine-associated pneumonia 1 month after inadvertent receipt of varicella vaccine.
- Published
- 2007
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