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Your search keyword '"Ubiquitins antagonists & inhibitors"' showing total 9 results

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9 results on '"Ubiquitins antagonists & inhibitors"'

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1. Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target.

2. The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth.

3. Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents.

4. Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor.

5. Inhibition of NEDD8-activating enzyme induces rereplication and apoptosis in human tumor cells consistent with deregulating CDT1 turnover.

6. NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cells.

7. The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.

8. Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through S-nitrosylation and inhibition of Bcl-2 ubiquitination.

9. Human THP-1 monocytic leukemic cells induced to undergo monocytic differentiation by bryostatin 1 are refractory to proteasome inhibitor-induced apoptosis.

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