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Start Over Author "Aifantis, Iannis" Publisher american association for cancer research (aacr)
46 results on '"Aifantis, Iannis"'

2. Supplementary Methods from Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Author

Glytsou, Christina, primary, Chen, Xufeng, primary, Zacharioudakis, Emmanouil, primary, Al-Santli, Wafa, primary, Zhou, Hua, primary, Nadorp, Bettina, primary, Lee, Soobeom, primary, Lasry, Audrey, primary, Sun, Zhengxi, primary, Papaioannou, Dimitrios, primary, Cammer, Michael, primary, Wang, Kun, primary, Zal, Tomasz, primary, Zal, Malgorzata Anna, primary, Carter, Bing Z., primary, Ishizawa, Jo, primary, Tibes, Raoul, primary, Tsirigos, Aristotelis, primary, Andreeff, Michael, primary, Gavathiotis, Evripidis, primary, and Aifantis, Iannis, primary

Published
2023
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3. Supplementary Figures 1-7 from Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Author

Glytsou, Christina, primary, Chen, Xufeng, primary, Zacharioudakis, Emmanouil, primary, Al-Santli, Wafa, primary, Zhou, Hua, primary, Nadorp, Bettina, primary, Lee, Soobeom, primary, Lasry, Audrey, primary, Sun, Zhengxi, primary, Papaioannou, Dimitrios, primary, Cammer, Michael, primary, Wang, Kun, primary, Zal, Tomasz, primary, Zal, Malgorzata Anna, primary, Carter, Bing Z., primary, Ishizawa, Jo, primary, Tibes, Raoul, primary, Tsirigos, Aristotelis, primary, Andreeff, Michael, primary, Gavathiotis, Evripidis, primary, and Aifantis, Iannis, primary

Published
2023
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4. Abstract A20: Inflammation remodels the immune microenvironment in acute myeloid leukemia

Author

Lasry, Audrey, primary, Nadorp, Bettina, additional, Fornerod, Maarten, additional, Nicolet, Deedra, additional, Wu, Huiyun, additional, Walker, Christopher J, additional, Sun, Zhengxi, additional, Witkowski, Matthew T, additional, Tikhonova, Anastasia N, additional, Guillamot, Maria, additional, Cayanan, Geraldine, additional, Yeaton, Anna, additional, Gruber, Tanja A, additional, Eisfeld, Ann-Kathrin, additional, and Aifantis, Iannis, additional

Published
2023
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5. Abstract A10: Targeting MHC-I antigen presentation for cancer immune evasion in acute myeloid leukemia

Author

Chen, Xufeng, primary, Lu, Qiao, additional, Zhou, Hua, additional, Liu, Jia, additional, Nadorp, Bettina, additional, Lasry, Audrey, additional, Sun, Zhengxi, additional, Zhang, Jiangyan, additional, Cammer, Michael, additional, Wang, Kun, additional, Ciantra, Zoe, additional, You, Jia, additional, Guo, Qianjin, additional, Zhang, Hongbing, additional, Sengupta, Debrup, additional, Boukhris, Ahmad, additional, Liu, Cheng, additional, Cresswell, Peter, additional, Dahia, Patricia L. M., additional, Wang, Jun, additional, and Aifantis, Iannis, additional

Published
2023
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7. Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia

Author

Glytsou, Christina, primary, Chen, Xufeng, additional, Zacharioudakis, Emmanouil, additional, Al-Santli, Wafa, additional, Zhou, Hua, additional, Nadorp, Bettina, additional, Lee, Soobeom, additional, Lasry, Audrey, additional, Sun, Zhengxi, additional, Papaioannou, Dimitrios, additional, Cammer, Michael, additional, Wang, Kun, additional, Zal, Tomasz, additional, Zal, Malgorzata Anna., additional, Carter, Bing Z., additional, Ishizawa, Jo, additional, Tibes, Raoul, additional, Tsirigos, Aristotelis, additional, Andreeff, Michael, additional, Gavathiotis, Evripidis, additional, and Aifantis, Iannis, additional

Published
2023
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9. Data from The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Author

Yeaton, Anna, primary, Cayanan, Geraldine, primary, Loghavi, Sanam, primary, Dolgalev, Igor, primary, Leddin, Emmett M., primary, Loo, Christian E., primary, Torabifard, Hedieh, primary, Nicolet, Deedra, primary, Wang, Jingjing, primary, Corrigan, Kate, primary, Paraskevopoulou, Varvara, primary, Starczynowski, Daniel T, primary, Wang, Eric, primary, Abdel-Wahab, Omar, primary, Viny, Aaron D, primary, Stone, Richard M., primary, Byrd, John C., primary, Guryanova, Olga A., primary, Kohli, Rahul M., primary, Cisneros, G. Andrés, primary, Tsirigos, Aristotelis, primary, Eisfeld, Ann-Kathrin, primary, Aifantis, Iannis, primary, and Guillamot, Maria, primary

Published
2023
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10. Supplementary Figure from The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Author

Yeaton, Anna, primary, Cayanan, Geraldine, primary, Loghavi, Sanam, primary, Dolgalev, Igor, primary, Leddin, Emmett M., primary, Loo, Christian E., primary, Torabifard, Hedieh, primary, Nicolet, Deedra, primary, Wang, Jingjing, primary, Corrigan, Kate, primary, Paraskevopoulou, Varvara, primary, Starczynowski, Daniel T, primary, Wang, Eric, primary, Abdel-Wahab, Omar, primary, Viny, Aaron D, primary, Stone, Richard M., primary, Byrd, John C., primary, Guryanova, Olga A., primary, Kohli, Rahul M., primary, Cisneros, G. Andrés, primary, Tsirigos, Aristotelis, primary, Eisfeld, Ann-Kathrin, primary, Aifantis, Iannis, primary, and Guillamot, Maria, primary

Published
2023
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11. Supplementary Data from The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Author

Yeaton, Anna, primary, Cayanan, Geraldine, primary, Loghavi, Sanam, primary, Dolgalev, Igor, primary, Leddin, Emmett M., primary, Loo, Christian E., primary, Torabifard, Hedieh, primary, Nicolet, Deedra, primary, Wang, Jingjing, primary, Corrigan, Kate, primary, Paraskevopoulou, Varvara, primary, Starczynowski, Daniel T, primary, Wang, Eric, primary, Abdel-Wahab, Omar, primary, Viny, Aaron D, primary, Stone, Richard M., primary, Byrd, John C., primary, Guryanova, Olga A., primary, Kohli, Rahul M., primary, Cisneros, G. Andrés, primary, Tsirigos, Aristotelis, primary, Eisfeld, Ann-Kathrin, primary, Aifantis, Iannis, primary, and Guillamot, Maria, primary

Published
2023
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12. Data from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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13. Supplementary Table 10 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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14. Supplementary Table S10 from BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells

Author

Valls, Ester, primary, Lobry, Camille, primary, Geng, Huimin, primary, Wang, Ling, primary, Cardenas, Mariano, primary, Rivas, Martín, primary, Cerchietti, Leandro, primary, Oh, Philmo, primary, Yang, Shao Ning, primary, Oswald, Erin, primary, Graham, Camille W., primary, Jiang, Yanwen, primary, Hatzi, Katerina, primary, Agirre, Xabier, primary, Perkey, Eric, primary, Li, Zhuoning, primary, Tam, Wayne, primary, Bhatt, Kamala, primary, Leonard, John P., primary, Zweidler-McKay, Patrick A., primary, Maillard, Ivan, primary, Elemento, Olivier, primary, Ci, Weimin, primary, Aifantis, Iannis, primary, and Melnick, Ari, primary

Published
2023
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15. Supplementary Table 8 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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16. Supplementary Table 7 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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17. Supplementary Table 2 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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18. Supplementary Table 2 from Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

Author

Chen, Xufeng, primary, Glytsou, Christina, primary, Zhou, Hua, primary, Narang, Sonali, primary, Reyna, Denis E., primary, Lopez, Andrea, primary, Sakellaropoulos, Theodore, primary, Gong, Yixiao, primary, Kloetgen, Andreas, primary, Yap, Yoon Sing, primary, Wang, Eric, primary, Gavathiotis, Evripidis, primary, Tsirigos, Aristotelis, primary, Tibes, Raoul, primary, and Aifantis, Iannis, primary

Published
2023
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19. Supplementary Methods, Figures 1 - 8, Table 5 from BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells

Author

Valls, Ester, primary, Lobry, Camille, primary, Geng, Huimin, primary, Wang, Ling, primary, Cardenas, Mariano, primary, Rivas, Martín, primary, Cerchietti, Leandro, primary, Oh, Philmo, primary, Yang, Shao Ning, primary, Oswald, Erin, primary, Graham, Camille W., primary, Jiang, Yanwen, primary, Hatzi, Katerina, primary, Agirre, Xabier, primary, Perkey, Eric, primary, Li, Zhuoning, primary, Tam, Wayne, primary, Bhatt, Kamala, primary, Leonard, John P., primary, Zweidler-McKay, Patrick A., primary, Maillard, Ivan, primary, Elemento, Olivier, primary, Ci, Weimin, primary, Aifantis, Iannis, primary, and Melnick, Ari, primary

Published
2023
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20. Supplementary Table 1 from Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

Author

Chen, Xufeng, primary, Glytsou, Christina, primary, Zhou, Hua, primary, Narang, Sonali, primary, Reyna, Denis E., primary, Lopez, Andrea, primary, Sakellaropoulos, Theodore, primary, Gong, Yixiao, primary, Kloetgen, Andreas, primary, Yap, Yoon Sing, primary, Wang, Eric, primary, Gavathiotis, Evripidis, primary, Tsirigos, Aristotelis, primary, Tibes, Raoul, primary, and Aifantis, Iannis, primary

Published
2023
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21. Data from Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

Author

Chen, Xufeng, primary, Glytsou, Christina, primary, Zhou, Hua, primary, Narang, Sonali, primary, Reyna, Denis E., primary, Lopez, Andrea, primary, Sakellaropoulos, Theodore, primary, Gong, Yixiao, primary, Kloetgen, Andreas, primary, Yap, Yoon Sing, primary, Wang, Eric, primary, Gavathiotis, Evripidis, primary, Tsirigos, Aristotelis, primary, Tibes, Raoul, primary, and Aifantis, Iannis, primary

Published
2023
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22. Supplementary Table 6 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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23. Supplementary Table 9 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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24. Supplementary Table 4 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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25. Supplementary Figures and Figure Legends from Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

Author

Chen, Xufeng, primary, Glytsou, Christina, primary, Zhou, Hua, primary, Narang, Sonali, primary, Reyna, Denis E., primary, Lopez, Andrea, primary, Sakellaropoulos, Theodore, primary, Gong, Yixiao, primary, Kloetgen, Andreas, primary, Yap, Yoon Sing, primary, Wang, Eric, primary, Gavathiotis, Evripidis, primary, Tsirigos, Aristotelis, primary, Tibes, Raoul, primary, and Aifantis, Iannis, primary

Published
2023
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26. Supplementary Table 5 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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27. Data from BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells

Author

Valls, Ester, primary, Lobry, Camille, primary, Geng, Huimin, primary, Wang, Ling, primary, Cardenas, Mariano, primary, Rivas, Martín, primary, Cerchietti, Leandro, primary, Oh, Philmo, primary, Yang, Shao Ning, primary, Oswald, Erin, primary, Graham, Camille W., primary, Jiang, Yanwen, primary, Hatzi, Katerina, primary, Agirre, Xabier, primary, Perkey, Eric, primary, Li, Zhuoning, primary, Tam, Wayne, primary, Bhatt, Kamala, primary, Leonard, John P., primary, Zweidler-McKay, Patrick A., primary, Maillard, Ivan, primary, Elemento, Olivier, primary, Ci, Weimin, primary, Aifantis, Iannis, primary, and Melnick, Ari, primary

Published
2023
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28. Supplementary Figures S1-15 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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29. Supplementary Table 3 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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30. Supplementary Tables and Methods from Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

Author

Chen, Xufeng, primary, Glytsou, Christina, primary, Zhou, Hua, primary, Narang, Sonali, primary, Reyna, Denis E., primary, Lopez, Andrea, primary, Sakellaropoulos, Theodore, primary, Gong, Yixiao, primary, Kloetgen, Andreas, primary, Yap, Yoon Sing, primary, Wang, Eric, primary, Gavathiotis, Evripidis, primary, Tsirigos, Aristotelis, primary, Tibes, Raoul, primary, and Aifantis, Iannis, primary

Published
2023
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31. Supplementary Table 4 from Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

Author

Chen, Xufeng, primary, Glytsou, Christina, primary, Zhou, Hua, primary, Narang, Sonali, primary, Reyna, Denis E., primary, Lopez, Andrea, primary, Sakellaropoulos, Theodore, primary, Gong, Yixiao, primary, Kloetgen, Andreas, primary, Yap, Yoon Sing, primary, Wang, Eric, primary, Gavathiotis, Evripidis, primary, Tsirigos, Aristotelis, primary, Tibes, Raoul, primary, and Aifantis, Iannis, primary

Published
2023
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32. Supplementary Table 3 from Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

Author

Chen, Xufeng, primary, Glytsou, Christina, primary, Zhou, Hua, primary, Narang, Sonali, primary, Reyna, Denis E., primary, Lopez, Andrea, primary, Sakellaropoulos, Theodore, primary, Gong, Yixiao, primary, Kloetgen, Andreas, primary, Yap, Yoon Sing, primary, Wang, Eric, primary, Gavathiotis, Evripidis, primary, Tsirigos, Aristotelis, primary, Tibes, Raoul, primary, and Aifantis, Iannis, primary

Published
2023
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33. The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Author

Yeaton, Anna, primary, Cayanan, Geraldine, additional, Loghavi, Sanam, additional, Dolgalev, Igor, additional, Leddin, Emmett M., additional, Loo, Christian E., additional, Torabifard, Hedieh, additional, Nicolet, Deedra, additional, Wang, Jingjing, additional, Corrigan, Kate, additional, Paraskevopoulou, Varvara, additional, Starczynowski, Daniel T, additional, Wang, Eric, additional, Abdel-Wahab, Omar, additional, Viny, Aaron D, additional, Stone, Richard M., additional, Byrd, John C., additional, Guryanova, Olga A., additional, Kohli, Rahul M., additional, Cisneros, G. Andrés, additional, Tsirigos, Aristotelis, additional, Eisfeld, Ann-Kathrin, additional, Aifantis, Iannis, additional, and Guillamot, Maria, additional

Published
2022
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34. Abstract PR04: Epigenetic silencing of CDR1as drives IGF2BP3-mediated melanoma invasion and metastasis

Author

Hanniford, Douglas, primary, Ulloa-Morales, Alejandro, additional, Sánchez-Sendra, Beatriz, additional, Karz, Alcida, additional, Moubarak, Rana, additional, Tabaglio, Tommaso, additional, Berzoti-Coelho, Maria Gabriela, additional, Davalos, Veronica, additional, Wu, Pamela, additional, Vasudevaraja, Varshini, additional, Kloetgen, Andreas, additional, Lilja, Karin, additional, Imig, Jochen, additional, Monteagudo, Carlos, additional, Guccione, Ernesto, additional, Tsirigos, Aristotelis, additional, Osman, Iman, additional, Aifantis, Iannis, additional, and Hernando, Eva, additional

Published
2020
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35. Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, additional, Wang, Eric, additional, Lorch, Adam H., additional, Serafin, Valentina, additional, Cho, Byoung-Kyu, additional, Gutierrez Diaz, Blanca T., additional, Calvo, Julien, additional, Fang, Celestia, additional, Khodadadi-Jamayran, Alireza, additional, Tabaglio, Tommaso, additional, Marier, Christian, additional, Kuchmiy, Anna, additional, Sun, Limin, additional, Yacu, George, additional, Filip, Szymon K., additional, Jin, Qi, additional, Takahashi, Yoh-Hei, additional, Amici, David R., additional, Rendleman, Emily J., additional, Rawat, Radhika, additional, Bresolin, Silvia, additional, Paganin, Maddalena, additional, Zhang, Cheng, additional, Li, Hu, additional, Kandela, Irawati, additional, Politanska, Yuliya, additional, Abdala-Valencia, Hiam, additional, Mendillo, Marc L., additional, Zhu, Ping, additional, Palhais, Bruno, additional, Van Vlierberghe, Pieter, additional, Taghon, Tom, additional, Aifantis, Iannis, additional, Goo, Young Ah, additional, Guccione, Ernesto, additional, Heguy, Adriana, additional, Tsirigos, Aristotelis, additional, Wee, Keng Boon, additional, Mishra, Rama K., additional, Pflumio, Francoise, additional, Accordi, Benedetta, additional, Basso, Giuseppe, additional, and Ntziachristos, Panagiotis, additional

Published
2020
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36. Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

Author

Chen, Xufeng, primary, Glytsou, Christina, additional, Zhou, Hua, additional, Narang, Sonali, additional, Reyna, Denis E., additional, Lopez, Andrea, additional, Sakellaropoulos, Theodore, additional, Gong, Yixiao, additional, Kloetgen, Andreas, additional, Yap, Yoon Sing, additional, Wang, Eric, additional, Gavathiotis, Evripidis, additional, Tsirigos, Aristotelis, additional, Tibes, Raoul, additional, and Aifantis, Iannis, additional

Published
2019
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37. TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis

Author

Dominguez, Pilar M., primary, Ghamlouch, Hussein, additional, Rosikiewicz, Wojciech, additional, Kumar, Parveen, additional, Béguelin, Wendy, additional, Fontán, Lorena, additional, Rivas, Martín A., additional, Pawlikowska, Patrycja, additional, Armand, Marine, additional, Mouly, Enguerran, additional, Torres-Martin, Miguel, additional, Doane, Ashley S., additional, Calvo Fernandez, María T., additional, Durant, Matt, additional, Della-Valle, Veronique, additional, Teater, Matt, additional, Cimmino, Luisa, additional, Droin, Nathalie, additional, Tadros, Saber, additional, Motanagh, Samaneh, additional, Shih, Alan H., additional, Rubin, Mark A., additional, Tam, Wayne, additional, Aifantis, Iannis, additional, Levine, Ross L., additional, Elemento, Olivier, additional, Inghirami, Giorgio, additional, Green, Michael R., additional, Figueroa, Maria E., additional, Bernard, Olivier A., additional, Aoufouchi, Said, additional, Li, Sheng, additional, Shaknovich, Rita, additional, and Melnick, Ari M., additional

Published
2018
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38. BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells

Author

Valls, Ester, primary, Lobry, Camille, additional, Geng, Huimin, additional, Wang, Ling, additional, Cardenas, Mariano, additional, Rivas, Martín, additional, Cerchietti, Leandro, additional, Oh, Philmo, additional, Yang, Shao Ning, additional, Oswald, Erin, additional, Graham, Camille W., additional, Jiang, Yanwen, additional, Hatzi, Katerina, additional, Agirre, Xabier, additional, Perkey, Eric, additional, Li, Zhuoning, additional, Tam, Wayne, additional, Bhatt, Kamala, additional, Leonard, John P., additional, Zweidler-McKay, Patrick A., additional, Maillard, Ivan, additional, Elemento, Olivier, additional, Ci, Weimin, additional, Aifantis, Iannis, additional, and Melnick, Ari, additional

Published
2017
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41. Abstract A06: The chemokine receptor CXCR4 is essential for the maintenance of T cell acute lymphoblastic leukemia.

Author

Pitt, Lauren A., primary, Tikhonova, Anastasia N., additional, Trimarchi, Thomas, additional, King, Bryan, additional, Hu, Hai, additional, Gong, Yixiao, additional, Tsirigos, Aris, additional, Sanchez-Martin, Marta, additional, Littman, Dan R., additional, Ferrando, Adolfo, additional, Morrison, Sean J., additional, Fooksman, David R., additional, Aifantis, Iannis, additional, and Schwab, Susan, additional

Published
2015
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43. Abstract PR03: Delineating the roles of lysine 27 methylation-associated epigenetic modulators in T cell leukemia

Author

G. Grant Welstead, Rab K. Prinjha, Pieter Van Vlierberghe, Thomas Trimarchi, Aifantis Iannis, Sofia Bakogianni, Adolfo A. Ferrando, Panagiotis Ntziachristos, Luyao Xu, Charles G. Mullighan, and Rudolf Jaenisch

Subjects
Cancer Research, biology, T-cell leukemia, Cancer, Context (language use), Methylation, medicine.disease, Histone, Oncology, Immunology, biology.protein, medicine, Cancer research, Demethylase, Epigenetics, PRC2
Abstract

The cure rate for childhood acute lymphoblastic leukemia (ALL) has dramatically improved, yet up to 25% of patients experience disease recurrence. T cell ALL (T-ALL) represents 15% of pediatric and 25% of adult ALL and it is classified as a high-risk type of ALL. The aim of the hitherto studies is to specifically block the effects of cancer inducing oncogenes. Recently, we identified inactivating mutations of the polycomb repressive complex 2 (PRC2), the “writer” of Histone 3 lysine 27 methylation, in primary samples from human patients revealing a tumor suppressor role for the complex in T-ALL. Extending our work on the H3K27me3 mark, we now show the oncogenic role for the Jumonji d3 (JMJD3) demethylase. Functionally, genomic ablation of the JMJD3 modulator as well as targeting with a specific inhibitor, GSKJ4, leads to apoptosis and cell cycle arrest of T-ALL lines and primary cells. Genetic ablation of JMJD3 leads to slower initiation of the disease with significantly improved survival rates of the mice. Surprisingly, UTX acts as a tumor suppressor in the context of the same disease, as part of different transcriptional complexes, and we found that it is genetically inactivated in T-ALL patients. Importantly, in light of recent developments on novel epigenetic inhibitors against JMJD3, these findings pave the way to specific pharmacological targeting of T cell leukemia. Citation Format: Panagiotis Ntziachristos, Grant Welstead, Thomas Trimarchi, Sofia Bakogianni, Luyao Xu, Pieter Van Vlierberghe, Rab Prinjha, Adolfo Ferrando, Rudolf Jaenisch, Charles Mullighan, Aifantis Iannis. Delineating the roles of lysine 27 methylation-associated epigenetic modulators in T cell leukemia. [abstract]. In: Proceedings of the AACR Special Conference on Hematologic Malignancies: Translating Discoveries to Novel Therapies; Sep 20-23, 2014; Philadelphia, PA. Philadelphia (PA): AACR; Clin Cancer Res 2015;21(17 Suppl):Abstract nr PR03.

Published
2015

44. Abstract B24: Delineating the roles of lysine 27 methylation-associated epigenetic modulators in T cell leukemia

Author

Sofia Bakogianni, Pieter Van Vlierberghe, Thomas Trimarchi, Charles G. Mullighan, Rudolf Jaenisch, Panagiotis Ntziachristos, Rab K. Prinjha, G. Grant Welstead, Luyao Xu, Adolfo A. Ferrando, and Aifantis Iannis

Subjects
Cancer Research, Oncology, Lysine, T-cell leukemia, Cancer research, Epigenetics, Methylation, Biology
Abstract

This abstract is being presented as a short talk. A full abstract is printed in the Proffered Abstracts section (PR03) of the Conference Proceedings. Citation Format: Panagiotis Ntziachristos, Grant Welstead, Thomas Trimarchi, Sofia Bakogianni, Luyao Xu, Pieter Van Vlierberghe, Rab Prinjha, Adolfo Ferrando, Rudolf Jaenisch, Charles Mullighan, Aifantis Iannis. Delineating the roles of lysine 27 methylation-associated epigenetic modulators in T cell leukemia. [abstract]. In: Proceedings of the AACR Special Conference on Hematologic Malignancies: Translating Discoveries to Novel Therapies; Sep 20-23, 2014; Philadelphia, PA. Philadelphia (PA): AACR; Clin Cancer Res 2015;21(17 Suppl):Abstract nr B24.

Published
2015

45. Abstract A07: Characterizing the specific oncogenic and tumor suppressor roles of H3K27me3 epigenetic modulators in T cell leukemia

Author

Ntziachristos, Panagiotis, primary, Tsirigos, Aris, additional, Trimarchi, Thomas, additional, Loizou, Evangelia, additional, Luyao, Xu, additional, Vlierberghe, Pieter Van, additional, King, Bryan, additional, Welstead, Grant, additional, Mullighan, Charles, additional, Jaenisch, Rudolf, additional, Ferrando, Adolfo, additional, and Aifantis, Iannis, additional

Published
2013
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