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Start Over Author "Noro,Rintaro" Publisher american association for cancer research (aacr)
20 results on '"Noro,Rintaro"'

2. Supplemental materials and methods from Inhibition of ABCB1 Overcomes Cancer Stem Cell–like Properties and Acquired Resistance to MET Inhibitors in Non–Small Cell Lung Cancer

Author

Sugano, Teppei, primary, Seike, Masahiro, primary, Noro, Rintaro, primary, Soeno, Chie, primary, Chiba, Mika, primary, Zou, Fenfei, primary, Nakamichi, Shinji, primary, Nishijima, Nobuhiko, primary, Matsumoto, Masaru, primary, Miyanaga, Akihiko, primary, Kubota, Kaoru, primary, and Gemma, Akihiko, primary

Published
2023
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3. Supplemental figure legends from Inhibition of ABCB1 Overcomes Cancer Stem Cell–like Properties and Acquired Resistance to MET Inhibitors in Non–Small Cell Lung Cancer

Author

Sugano, Teppei, primary, Seike, Masahiro, primary, Noro, Rintaro, primary, Soeno, Chie, primary, Chiba, Mika, primary, Zou, Fenfei, primary, Nakamichi, Shinji, primary, Nishijima, Nobuhiko, primary, Matsumoto, Masaru, primary, Miyanaga, Akihiko, primary, Kubota, Kaoru, primary, and Gemma, Akihiko, primary

Published
2023
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4. Supplementary Figure 2 from MiR-134/487b/655 Cluster Regulates TGF-β–Induced Epithelial–Mesenchymal Transition and Drug Resistance to Gefitinib by Targeting MAGI2 in Lung Adenocarcinoma Cells

Author

Kitamura, Kazuhiro, primary, Seike, Masahiro, primary, Okano, Tetsuya, primary, Matsuda, Kuniko, primary, Miyanaga, Akihiko, primary, Mizutani, Hideaki, primary, Noro, Rintaro, primary, Minegishi, Yuji, primary, Kubota, Kaoru, primary, and Gemma, Akihiko, primary

Published
2023
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5. Supplemental Table 1. Supplemental Table 2. Supplemental Table 3. from Inhibition of ABCB1 Overcomes Cancer Stem Cell–like Properties and Acquired Resistance to MET Inhibitors in Non–Small Cell Lung Cancer

Author

Sugano, Teppei, primary, Seike, Masahiro, primary, Noro, Rintaro, primary, Soeno, Chie, primary, Chiba, Mika, primary, Zou, Fenfei, primary, Nakamichi, Shinji, primary, Nishijima, Nobuhiko, primary, Matsumoto, Masaru, primary, Miyanaga, Akihiko, primary, Kubota, Kaoru, primary, and Gemma, Akihiko, primary

Published
2023
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6. Data from Inhibition of ABCB1 Overcomes Cancer Stem Cell–like Properties and Acquired Resistance to MET Inhibitors in Non–Small Cell Lung Cancer

Author

Sugano, Teppei, primary, Seike, Masahiro, primary, Noro, Rintaro, primary, Soeno, Chie, primary, Chiba, Mika, primary, Zou, Fenfei, primary, Nakamichi, Shinji, primary, Nishijima, Nobuhiko, primary, Matsumoto, Masaru, primary, Miyanaga, Akihiko, primary, Kubota, Kaoru, primary, and Gemma, Akihiko, primary

Published
2023
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7. Supplemental Figure 1,Supplemental Figure 2,Supplemental Figure 3, Supplemental Figure 4 from Inhibition of ABCB1 Overcomes Cancer Stem Cell–like Properties and Acquired Resistance to MET Inhibitors in Non–Small Cell Lung Cancer

Author

Sugano, Teppei, primary, Seike, Masahiro, primary, Noro, Rintaro, primary, Soeno, Chie, primary, Chiba, Mika, primary, Zou, Fenfei, primary, Nakamichi, Shinji, primary, Nishijima, Nobuhiko, primary, Matsumoto, Masaru, primary, Miyanaga, Akihiko, primary, Kubota, Kaoru, primary, and Gemma, Akihiko, primary

Published
2023
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8. Supplementary Figure 1 from MiR-134/487b/655 Cluster Regulates TGF-β–Induced Epithelial–Mesenchymal Transition and Drug Resistance to Gefitinib by Targeting MAGI2 in Lung Adenocarcinoma Cells

Author

Kitamura, Kazuhiro, primary, Seike, Masahiro, primary, Okano, Tetsuya, primary, Matsuda, Kuniko, primary, Miyanaga, Akihiko, primary, Mizutani, Hideaki, primary, Noro, Rintaro, primary, Minegishi, Yuji, primary, Kubota, Kaoru, primary, and Gemma, Akihiko, primary

Published
2023
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9. Supplementary Data from Urinary Metabolite Risk Biomarkers of Lung Cancer: A Prospective Cohort Study

Author

Haznadar, Majda, primary, Cai, Qiuyin, primary, Krausz, Kristopher W., primary, Bowman, Elise D., primary, Margono, Ezra, primary, Noro, Rintaro, primary, Thompson, Matthew D., primary, Mathé, Ewy A., primary, Munro, Heather M., primary, Steinwandel, Mark D., primary, Gonzalez, Frank J., primary, Blot, William J., primary, and Harris, Curtis C., primary

Published
2023
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10. Supplementary Fig. S1 from Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model

Author

Miyanaga, Akihiko, primary, Gemma, Akihiko, primary, Noro, Rintaro, primary, Kataoka, Kiyoko, primary, Matsuda, Kuniko, primary, Nara, Michiya, primary, Okano, Tetsuya, primary, Seike, Masahiro, primary, Yoshimura, Akinobu, primary, Kawakami, Akiko, primary, Uesaka, Haruka, primary, Nakae, Hiroki, primary, and Kudoh, Shoji, primary

Published
2023
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11. Abstract 3068: The glycoprotein inhibitors overcome the resistance of the topoisomerase inhibitors in small cell lung cancer

Author

Noro, Rintaro, primary, Omori, Miwako, additional, Fukuizumi, Aya, additional, Matsuda, kuniko, additional, Hirao, Mariko, additional, Takahashi, Satoshi, additional, Takano, Natsuki, additional, Nakamichi, Shinji, additional, Sugano, Teppei, additional, Miyanaga, Akihiko, additional, Minegishi, Yuji, additional, Seike, Masahiro, additional, Kubota, Kaoru, additional, and Gemma, Akihiko, additional

Published
2020
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12. Abstract 4208: HOXA9 methylation detection by droplet digital PCR and blood vessel invasion using FFPE tissues for prognostic stratification of stage I lung adenocarcinoma patients

Author

Lissa, Delphine, primary, Ishigame, Teruhide, additional, Noro, Rintaro, additional, Tucker, Marguerite J., additional, Bliskovsky, Valery, additional, Shema, Steven, additional, Bowman, Elise D., additional, Harris, Curtis C., additional, and Robles, Ana I., additional

Published
2018
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13. Abstract 3209: Polo-like kinase 1 as a new molecular target for small cell lung carcinoma

Author

Masahiro Seike, Akihiko Gemma, Kaoru Kubota, Akihiko Miyanaga, Noro Rintaro, and Fenfei Zou

Subjects
Oncology, Cancer Research, medicine.medical_specialty, business.industry, Kinase, Cell growth, Cancer, Volasertib, Polo-like kinase, medicine.disease, chemistry.chemical_compound, chemistry, Internal medicine, Cancer cell, medicine, Small Cell Lung Carcinoma, Lung cancer, business
Abstract

No target therapies are presently available in the treatment of small-cell lung cancer of Lung (SCLC). Therefore there is a need to develop new therapeutic agents. The protein kinases are a family of genes that play critical roles in various signaling pathways. Some cancer cells show addiction to constitutive activation of certain signaling pathways for proliferation and survival. To identify new drug targets for SCLC, we screened a panel of small interfering RNAs (siRNAs) that target 720 genes encoding human protein kinases and related proteins using SBC5 SCLC cell (SN38 (irinotecan hydrochloride) resistant cell). PLK1 inhibition suppressed cell proliferation strongest among 20 significant promising total genes using different 5 SCLC cells as a varidation study). PLK1 mRNA expression was significantly higher than other pathological phenotypes among 20 celllines and the 200 clinical samples consist of three independent cohorts. The patients with high PLK1 expresssion was significantly associated with poor prognosis in SCLC patients. Furthermore we investigated the change of SN 38 sensitivity and preventing from SN38 resistance after knockdown PLK1. Our results indicated that PLK1 inhibitor as BI 2536 and Volasertib, was a promising molecular target therapy for pharmacologic intervention in SCLC in both monotherapy and the combination therapy with SN38. Note: This abstract was not presented at the meeting. Citation Format: Noro Rintaro, Masahiro Seike, Fenfei Zou, Akihiko Miyanaga, Kaoru Kubota, Akihiko Gemma. Polo-like kinase 1 as a new molecular target for small cell lung carcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3209. doi:10.1158/1538-7445.AM2017-3209

Published
2017
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14. Urinary Metabolite Risk Biomarkers of Lung Cancer: A Prospective Cohort Study

Author

Haznadar, Majda, primary, Cai, Qiuyin, additional, Krausz, Kristopher W., additional, Bowman, Elise D., additional, Margono, Ezra, additional, Noro, Rintaro, additional, Thompson, Matthew D., additional, Mathé, Ewy A., additional, Munro, Heather M., additional, Steinwandel, Mark D., additional, Gonzalez, Frank J., additional, Blot, William J., additional, and Harris, Curtis C., additional

Published
2016
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15. Inhibition of ABCB1 Overcomes Cancer Stem Cell–like Properties and Acquired Resistance to MET Inhibitors in Non–Small Cell Lung Cancer

Author

Sugano, Teppei, primary, Seike, Masahiro, additional, Noro, Rintaro, additional, Soeno, Chie, additional, Chiba, Mika, additional, Zou, Fenfei, additional, Nakamichi, Shinji, additional, Nishijima, Nobuhiko, additional, Matsumoto, Masaru, additional, Miyanaga, Akihiko, additional, Kubota, Kaoru, additional, and Gemma, Akihiko, additional

Published
2015
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17. MiR-134/487b/655 Cluster Regulates TGF-β–Induced Epithelial–Mesenchymal Transition and Drug Resistance to Gefitinib by Targeting MAGI2 in Lung Adenocarcinoma Cells

Author

Kitamura, Kazuhiro, primary, Seike, Masahiro, additional, Okano, Tetsuya, additional, Matsuda, Kuniko, additional, Miyanaga, Akihiko, additional, Mizutani, Hideaki, additional, Noro, Rintaro, additional, Minegishi, Yuji, additional, Kubota, Kaoru, additional, and Gemma, Akihiko, additional

Published
2014
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19. Abstract 5548: High copy number of the MET gene predicts resistance to EGFR-TKI in non-small cell lung cancer patients.

Author

Noro, Rintaro, primary, Seike, Masahiro, additional, Soeno, Chie, additional, Matsuda, Kuniko, additional, Sugano, Teppei, additional, Nishijima, Nobuhiko, additional, Toyokawa, Masaru, additional, Kitamura, Kazuhiro, additional, Kosaihira, Seiji, additional, Minegishi, Yuji, additional, Yoshimura, Akinobu, additional, Kubota, Kaoru, additional, and Gemma, Akihiko, additional

Published
2012
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20. Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model

Author

Miyanaga, Akihiko, primary, Gemma, Akihiko, additional, Noro, Rintaro, additional, Kataoka, Kiyoko, additional, Matsuda, Kuniko, additional, Nara, Michiya, additional, Okano, Tetsuya, additional, Seike, Masahiro, additional, Yoshimura, Akinobu, additional, Kawakami, Akiko, additional, Uesaka, Haruka, additional, Nakae, Hiroki, additional, and Kudoh, Shoji, additional

Published
2008
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