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Start Over Author "Orlando, David A." Publisher american association for cancer research (aacr)
25 results on '"Orlando, David A."'

1. Supplementary Table S3: Median Survival By Cluster from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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2. Supplementary Table S2: mRNA Cluster Signatures from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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3. Supplementary Table S1: Sample mutations from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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4. Supplementary Table S4: Enhancer, mRNA, and SY-1425 EC50 in AML cell lines from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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5. Supplementary Table S2: mRNA Cluster Signatures from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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6. Supplementary Methods and Figure Legends from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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7. Supplementary Table S7: GREAT analysis from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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8. Supplementary Methods and Figure Legends from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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9. Data from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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10. Data from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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11. Supplementary Table S7: GREAT analysis from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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12. Supplementary Table S1: Sample mutations from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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13. Supplementary Figures from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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14. Supplementary Table S3: Median Survival By Cluster from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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15. Supplementary Figures from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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16. Supplementary Table S5 & 6: GSEA of SY-1425 response from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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17. Supplementary Table S5 & 6: GSEA of SY-1425 response from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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18. Supplementary Table S4: Enhancer, mRNA, and SY-1425 EC50 in AML cell lines from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, primary, Eaton, Matthew L., primary, Fiore, Chris, primary, Lee, Emily, primary, Lopez, Jeremy T., primary, Chen, Mei Wei, primary, Smith, Darren, primary, Chan, Steven M., primary, Koenig, Julie L., primary, Austgen, Kathryn, primary, Guenther, Matthew G., primary, Orlando, David A., primary, Lovén, Jakob, primary, Fritz, Christian C., primary, and Majeti, Ravindra, primary

Published
2023
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21. Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7

Author

Hu, Shanhu, primary, Marineau, Jason J., additional, Rajagopal, Nisha, additional, Hamman, Kristin B., additional, Choi, Yoon Jong, additional, Schmidt, Darby R., additional, Ke, Nan, additional, Johannessen, Liv, additional, Bradley, Michael J., additional, Orlando, David A., additional, Alnemy, Sydney R., additional, Ren, Yixuan, additional, Ciblat, Stephane, additional, Winter, Dana K., additional, Kabro, Anzhelika, additional, Sprott, Kevin T., additional, Hodgson, J. Graeme, additional, Fritz, Christian C., additional, Carulli, John P., additional, di Tomaso, Emmanuelle, additional, and Olson, Eric R., additional

Published
2019
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22. Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

Author

McKeown, Michael R., primary, Corces, M. Ryan, additional, Eaton, Matthew L., additional, Fiore, Chris, additional, Lee, Emily, additional, Lopez, Jeremy T., additional, Chen, Mei Wei, additional, Smith, Darren, additional, Chan, Steven M., additional, Koenig, Julie L., additional, Austgen, Kathryn, additional, Guenther, Matthew G., additional, Orlando, David A., additional, Lovén, Jakob, additional, Fritz, Christian C., additional, and Majeti, Ravindra, additional

Published
2017
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