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Start Over Author "Beng Lee Lim" Publisher american association for the advancement of science
1 results on '"Beng Lee Lim"'

1. Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.

Author

Wan Ni Chia, Chee Wah Tan, Tan, Aaron Wai Kit, Young, Barnaby, Starr, Tyler N., Lopez, Ester, Fibriansah, Guntur, Barr, Jennifer, Cheng, Samuel, Yeoh, Aileen Ying-Yan, Wee Chee Yap, Beng Lee Lim, Thiam-Seng Ng, Wan Rong Sia, Feng Zhu, Shiwei Chen, Jinyan Zhang, Kwek, Madeline Sheng Si, Greaney, Allison J., and Chen, Mark

Subjects
*MONOCLONAL antibodies, *SARS-CoV-2, *FC receptors, *COVID-19, *CLASSICAL swine fever
Abstract

The article focuses on a study conducted to characterize powerful monoclonal antibodies (mAbs) from a vaccinated severe acute respiratory syndrome coronavirus (SARS-CoV) survivor. It found that one specific mAb (E7) showed remarkable potency and coverage against huACE2-dependent sarbecoviruses, with unique binding characteristics revealed through mutagenesis and cryo-electron microscopy.

Published
2023
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