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Your search keyword '"GUO, J.-L."' showing total 1 results
Start Over Author "GUO, J.-L." Publisher american association for the advancement of science
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1. Modular, tissue-specific, and biodegradable hydrogel cross-linkers for tissue engineering.

Author

Guo, J. L., Kim, Y. S., Xie, V. Y., Smith, B. T., Watson, E., Pearce, H. A., Mikos, A. G., Lam, J., and Engel, P. S.

Subjects
*HYDROGELS, *TISSUE engineering, *MACROMOLECULAR dynamics, *BIOMOLECULES, *CELLULAR control mechanisms
Abstract

The article reports that synthetic hydrogels are investigated extensively in tissue engineering for their tunable physicochemical properties but are bioinert and lack the tissue-specific cues to produce appropriate biological responses. The authors we have developed a modular hydrogel cross-linker that can be functionalized with small peptide-based cues and large macromolecular cues simply by mixing PdBT in water with the appropriate biomolecules at room temperature.

Published
2019
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