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Your search keyword '"Hou, Xinjun"' showing total 7 results

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7 results on '"Hou, Xinjun"'

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1. Current and Future Roles of Artificial Intelligence in Medicinal Chemistry Synthesis.

2. Discovery and Characterizationof a Novel DihydroisoxazoleClass of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid (AMPA) Receptor Potentiators.

3. Designand Selection Parameters to Accelerate theDiscovery of Novel Central Nervous System Positron Emission Tomography(PET) Ligands and Their Application in the Development of a NovelPhosphodiesterase 2A PET Ligand.

4. Application of Structure-BasedDrug Design and ParallelChemistry to Identify Selective, Brain Penetrant, In Vivo Active Phosphodiesterase9A Inhibitors.

5. Design and Discovery of6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (PF-04447943),a Selective Brain Penetrant PDE9A Inhibitor for the Treatment of...

7. Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia.

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