Search

Your search keyword '"Scott, Peter"' showing total 1 results
1 results on '"Scott, Peter"'

1. Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids.

Author

Mossine, Andrew V., Brooks, Allen F., Makaravage, Katarina J., Miller, Jason M., Naoko Ichiishi, Sanford, Melanie S., and Scott, Peter J. H.

Subjects
*AROMATIC compound synthesis, *COPPER compounds, *FLUORINATION, *BORONIC acids, *GLUTAMATE receptors
Abstract

A copper-mediated radiofluorination of aryl- and vinylboronic acids with K18F is described. This method exhibits high functional group tolerance and is effective for the radiofluorination of a range of electron-deficient, -neutral, and -rich aryl-, heteroaryl-, and vinylboronic acids. This method has been applied to the synthesis of [18F]FPEB, a PET radiotracer for quantifying metabotropic glutamate 5 receptors. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results