37 results on '"Spring, David R."'
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2. Diversity-oriented synthesis of biaryl-containing medium rings using a one bed/one stock solution platform
3. Targeting a Novel KRAS Binding Site: Application of One-Component Stapling of Small (5–6-mer) Peptides.
4. Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells.
5. [Zn.sup.2+]-triggered amide tautomerization produces a highly [Zn.sup.2+]-selective, cell-permeable, and ratiometric fluorescent sensor
6. Strategies for the Diversity-Oriented Synthesis of Macrocycles.
7. Spirocycles as Rigidified sp3‑Rich Scaffolds for a Fragment Collection.
8. Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides.
9. Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1'-Biphenyl-2,2',6,6'-tetrol.
10. Structural and Functional Characterization of Malate Synthase G from Opportunistic Pathogen Pseudomonas aeruginosa.
11. Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.
12. Towards diversity-oriented, stereoselective syntheses of biaryl-or bis(aryl)metal-containing medium rings
13. Bioinspired Total Synthesis of Bussealin E.
14. Enantioselective Synthesis of Chromanones via a Peptidic Phosphane Catalyzed Rauhut-Currier Reaction.
15. The Useof Chlorobenzene as a Probe Molecule in MolecularDynamics Simulations.
16. How DiverseAre Diversity Assessment Methods? A ComparativeAnalysis and Benchmarking of Molecular Descriptor Space.
17. Concise Copper-Catalyzed Synthesis of Tricyclic Biaryl Ether-Linked Aza-Heterocyclic Ring Systems.
18. Ligand Binding Kinetics of the Quorum Sensing Regulator PqsR.
19. A Lysosome-Targetable Fluorescent Probe for Imaging Hydrogen Sulfide in Living Cells.
20. Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and AI-2 Quorum Sensing Pathways.
21. Stereocontrolled Semisyntheses of Elliptone and 12aβ-Hydroxyelliptone
22. Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor.
23. Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.
24. Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction.
25. Development of a Novel Cell-Permeable Protein-Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1.
26. Spirocycles as Rigidified sp 3 -Rich Scaffolds for a Fragment Collection.
27. Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.
28. The Application of Ligand-Mapping Molecular Dynamics Simulations to the Rational Design of Peptidic Modulators of Protein-Protein Interactions.
29. The use of chlorobenzene as a probe molecule in molecular dynamics simulations.
30. High content screening of diverse compound libraries identifies potent modulators of tubulin dynamics.
31. How diverse are diversity assessment methods? A comparative analysis and benchmarking of molecular descriptor space.
32. Rational methods for the selection of diverse screening compounds.
33. Diversity-oriented synthesis of disubstituted alkenes using masked silanols.
34. Zn2+-triggered amide tautomerization produces a highly Zn2+-selective, cell-permeable, and ratiometric fluorescent sensor.
35. Total synthesis of sanguiin H-5.
36. Learning the language of bacteria.
37. Small-molecule screening: advances in microarraying and cell-imaging technologies.
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