1. Cyclodextrin-Based Nanogels for Stabilization and Sensing of Curcumin.
- Author
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Casulli, Maria Antonietta, Yan, Ruyu, Takeuchi, Satomi, Cesari, Andrea, Mancin, Fabrizio, Hayashita, Takashi, Hashimoto, Takeshi, and Taurino, Irene
- Abstract
Curcumin (CUR), a polyphenolic substance from turmeric, displays diverse medicinal properties. However, its instability poses challenges in detection. Cyclodextrin-based nanogels (CyDngs) offer a transformative solution, enhancing CUR's stability in aqueous solutions. Multisensing approaches involving fluorescence, electrochemistry, and NMR spectroscopy were employed, demonstrating CyDngs' pivotal role in CUR detection. Langmuir analysis revealed a binding constant of 1.4 × 10
4 M–1 for CyDngs, highlighting their effectiveness over native β-CyDs. The study emphasized CyDngs' superiority in stabilizing CUR and enabling reliable and sensitive detection with very diverse methods. [ABSTRACT FROM AUTHOR]- Published
- 2024
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