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Your search keyword '"Yi-Min She"' showing total 2 results
Start Over Author "Yi-Min She" Publisher american chemical society
2 results on '"Yi-Min She"'

1. Autocatalytic cleavage of myelin basic protein: An alternative to molecular mimicry

Author

D'Souza, Cheryl A., Wood, D. Denise, Yi-Min She, and Mocarello, Mario A.

Subjects
Myelin proteins -- Research, Multiple sclerosis -- Research, T cells -- Research, Biological sciences, Chemistry
Abstract

Myelin basic protein-component 1 (MBP-C1) from multiple sclerosis (MS) tissue is demonstrated to undergo autocatalytic cleavage at slightly alkaline pH. The importance of this cleavage mechanism is that it provides for a ready source of the immunodominant peptide for sensitization of T-cells.

Published
2005

2. Characterization and copper binding properties of human COMMD1 (MURR1)

Author

Narindrasorasak, Suree, Kulkarni, Prasad, Deschamps, Patrick, Yi-Min She, and Sarkar, Bidudhendra

Subjects
Cell metabolism -- Research, Homeostasis -- Research, Metalloproteins -- Structure, Metalloproteins -- Genetic aspects, Wilson's disease -- Genetic aspects, Wilson's disease -- Research, Biological sciences, Chemistry
Abstract

The characterization and specific copper binding properties of purified recombinant human copper metabolism gene MURR1 (mouse U2af1-rs1 region1) domain) (COMMD1) as well as that of the exon 2 product (COMMD-(61-154)) are studied. The results have helped in understanding the function of COMMD1 and COMMD(61-154), a product of exon 2 that is deleted in terriers affected by copper toxicosis, as a regulator of copper homeostasis.

Published
2007

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