Search

Your search keyword '"Geng, Xiu"' showing total 5 results
Start Over Author "Geng, Xiu" Publisher american chemical society (acs)
5 results on '"Geng, Xiu"'

1. Recombinant Porcine R-Spondin 1 Facilitates Intestinal Stem Cell Expansion along the Crypt–Villus Axis through Potentiating Wnt/β-Catenin Signaling in Homeostasis and Deoxynivalenol Injury

Author

Jia-yi Zhou, Geng-xiu Zan, Qiu-jie Zhu, Chun-qi Gao, Hui-chao Yan, and Xiu-qi Wang

Subjects
Mice, Swine, Stem Cells, Animals, Homeostasis, Humans, General Chemistry, Intestinal Mucosa, Trichothecenes, General Agricultural and Biological Sciences, Wnt Signaling Pathway, beta Catenin, Cell Proliferation
Abstract

R-spondin 1 (RSPO1) is a ligand for the intestinal stem cell (ISC) marker Lgr5 in the crypt, which functions to amplify canonical Wnt signaling to stimulate the division of ISCs. Despite the crucial role of recombinant human RSPO1 (rhRSPO1) in homeostasis and regeneration, little is known about RSPO1 among different species. Here, we cloned the porcine RSPO1 (pRSPO1) gene and obtained rpRSPO1 protein through the expression system of the recombinant

Published
2022

Catalog

Books, media, physical & digital resources
See catalog results