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Your search keyword '"Nianyu Huang"' showing total 4 results
Start Over Author "Nianyu Huang" Publisher american chemical society (acs)
4 results on '"Nianyu Huang"'

2. Stereoselective O-Glycosylation of Glycals with Arylboronic Acids Using Air as the Oxygen Source

Author

Qiuyuan Wang, Mengnan Lai, Huajun Luo, Keke Ren, Jingrui Wang, Nianyu Huang, Zhangshuang Deng, Kun Zou, and Hui Yao

Subjects
Organic Chemistry, Physical and Theoretical Chemistry, Biochemistry
Abstract

An open-air palladium-catalyzed O-glycosylation was developed using glycals and arylboronic acids with base additives at ambient conditions. The novel approach enabled facile access to various

Published
2022

3. Catalyst-Controlled Regiodivergent Synthesis of 1- and 3-Thiosugars with High Stereoselectivity and Chemoselectivity

Author

Kun Zou, Jiao Yang, Hui Yao, Mengnan Lai, Yuexin Liu, Nianyu Huang, and Hua-Jun Luo

Subjects
chemistry.chemical_classification, Glycosylation, Glycal, 010405 organic chemistry, chemistry.chemical_element, General Chemistry, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, Catalysis, 0104 chemical sciences, Thiosugars, chemistry.chemical_compound, chemistry, Stereoselectivity, Chemoselectivity, Cobalt, Palladium
Abstract

An effective regiodivergent synthesis toward 1- and 3-thiosugars was achieved through palladium and cobalt catalysis, respectively. β-1-Thiosugars were obtained from 3,4-O-carbonate-glycals and var...

Published
2021

4. Open-Air Stereoselective Construction of C-Aryl Glycosides

Author

Kun Zou, Feng Yongkui, Karwan Abdulmajed Othman, Mengnan Lai, Nianyu Huang, Hui Yao, Ming-Guo Liu, and Qiuyuan Wang

Subjects
Steric effects, 010405 organic chemistry, Decarboxylation, Aryl, Organic Chemistry, chemistry.chemical_element, Substrate (chemistry), Stereoisomerism, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, Catalysis, chemistry.chemical_compound, chemistry, Organic chemistry, Stereoselectivity, Physical and Theoretical Chemistry, Palladium
Abstract

A new methodology of stereoselective C-glycosylation has been developed with 3,4-O-carbonate glycals and boronic acids, catalyzed by 1,2-bis(phenylsulfinyl)ethane palladium(II) acetate under open-air conditions at room temperature. This mild method is simple in operation, wide in substrate range, and tolerant in alcoholic/phenolic hydroxyl and amino groups. High to excellent yields were observed for all substrates tested, with the driving force mainly contributed by decarboxylation. Meanwhile, the high 1,4-trans-selectivity was achieved by steric effects as proposed.

Published
2020

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