33 results on '"Spring, David R."'
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2. Spirocycles as Rigidified sp3-Rich Scaffolds for a Fragment Collection
3. Development of a Novel Cell-Permeable Protein-Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1
4. Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells
5. Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design
6. Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction
7. Development of a Novel Cell-Permeable Protein–Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1
8. Strategies for the Diversity-Oriented Synthesis of Macrocycles
9. Spirocycles as Rigidified sp3-Rich Scaffolds for a Fragment Collection
10. Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides
11. Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1′-Biphenyl-2,2′,6,6′-tetrol
12. Bioinspired Total Synthesis of Bussealin E
13. Stereocontrolled Semisyntheses of Elliptone and 12aβ-Hydroxyelliptone
14. Structural and Functional Characterization of Malate Synthase G from Opportunistic Pathogen Pseudomonas aeruginosa
15. Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase
16. The Application of Ligand-Mapping Molecular Dynamics Simulations to the Rational Design of Peptidic Modulators of Protein–Protein Interactions
17. Enantioselective Synthesis of Chromanones via a Peptidic Phosphane Catalyzed Rauhut–Currier Reaction
18. The Use of Chlorobenzene as a Probe Molecule in Molecular Dynamics Simulations
19. High Content Screening of Diverse Compound Libraries Identifies Potent Modulators of Tubulin Dynamics
20. How Diverse Are Diversity Assessment Methods? A Comparative Analysis and Benchmarking of Molecular Descriptor Space
21. Concise Copper-Catalyzed Synthesis of Tricyclic Biaryl Ether-Linked Aza-Heterocyclic Ring Systems
22. Ligand Binding Kinetics of the Quorum Sensing Regulator PqsR
23. A Lysosome-Targetable Fluorescent Probe for Imaging Hydrogen Sulfide in Living Cells
24. Rational Methods for the Selection of Diverse Screening Compounds
25. Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and AI-2 Quorum Sensing Pathways
26. Diversity-Oriented Synthesis of Disubstituted Alkenes Using Masked Silanols
27. Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor
28. Total Synthesis of Sanguiin H-5
29. Learning the Language of Bacteria
30. Small-Molecule Screening: Advances in Microarraying and Cell-Imaging Technologies
31. Diversity-Oriented Synthesis of Biaryl-Containing Medium Rings Using a One Bead/One Stock Solution Platform
32. Towards Diversity-Oriented, Stereoselective Syntheses of Biaryl- or Bis(aryl)metal-Containing Medium Rings
33. Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design
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