107 results on '"Turner, Nicholas"'
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2. Phage display against two-dimensional metal-organic nanosheets as a new route to highly selective biomolecular recognition surfaces
3. Biocatalysis in Drug Design: Engineered Reductive Aminases (RedAms) Are Used to Access Chiral Building Blocks with Multiple Stereocenters
4. Structure-Based Design of Small Imine Reductase Panels for Target Substrates
5. Multicomponent Synthesis of the SARS-CoV-2 Main Protease Inhibitor Nirmatrelvir
6. RetroBioCat Database: A Platform for Collaborative Curation and Automated Meta-Analysis of Biocatalysis Data
7. Biocatalytic and Chemo-Enzymatic Synthesis of Quinolines and 2-Quinolones by Monoamine Oxidase (MAO-N) and Horseradish Peroxidase (HRP) Biocatalysts
8. One-Pot Chemoenzymatic Cascade for the Enantioselective C(1)-Allylation of Tetrahydroisoquinolines
9. Discovery of an Imine Reductase for Reductive Amination of Carbonyl Compounds with Sterically Challenging Amines
10. A Reductive Aminase Switches to Imine Reductase Mode for a Bulky Amine Substrate
11. Structure-based design of biocatalytic panels for pharmaceuticals synthesis
12. Synthesis of Stereoenriched Piperidines via Chemo-Enzymatic Dearomatization of Activated Pyridines
13. The Time and Place for Nature in Drug Discovery
14. Three-Component Stereoselective Enzymatic Synthesis of Amino-Diols and Amino-Polyols
15. Biocatalysis: Improving Enzymatic Processes through Protein and Reaction Engineering
16. A Nanoconfined Four-Enzyme Cascade Simultaneously Driven by Electrical and Chemical Energy, with Built-in Rapid, Confocal Recycling of NADP(H) and ATP
17. Direct Analysis of Biotransformations with Mass Spectrometry – DiBT-MS
18. Chemoenzymatic Multicomponent Synthesis of Nirmatrelvir
19. Enzymatic N-Allylation of Primary and Secondary Amines Using Renewable Cinnamic Acids Enabled by Bacterial Reductive Aminases
20. Thioester Mediated Biocatalytic Amide Bond Synthesis with In Situ Thiol Recycling
21. An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir
22. One-Step Biocatalytic Synthesis of Sustainable Surfactants Using Selective Amide Bond Formation
23. Engineering a Cytidine Aminotransferase for Biocatalytic Production of the Antiviral Molnupiravir
24. Synthesis of stereoenriched piperidines via chemo-enzymatic dearomatization of activated pyridines
25. Exploiting Bidirectional Electrocatalysis by a Nanoconfined Enzyme Cascade to Drive and Control Enantioselective Reactions
26. Rapid Screening of Diverse Biotransformations for Enzyme Evolution
27. Production of High Value Amine Intermediates via Biocatalytic Cascades in Continuous Flow
28. A Biocatalytic Approach to a Key Intermediate for the Synthesis of the COVID-19 Experimental Drug Molnupiravir
29. Rapid Screening of Diverse Biotransformations for Enzyme Evolution
30. Biocatalytic Conversion of 5-Hydroxymethylfurfural by Galactose Oxidase: Toward Scalable Technology Using Integrated Process and Enzyme Engineering
31. Biocatalytic Monoacylation of Symmetrical Diamines and Its Application to the Synthesis of Pharmaceutically Relevant Amides
32. Coupling Droplet Microfluidics with Mass Spectrometry for Ultrahigh-Throughput Analysis of Complex Mixtures up to and above 30 Hz
33. RetroBioCat: Computer-Aided Synthesis Planning for Biocatalytic Reactions and Cascades
34. Coupling Droplet Microfluidics with Mass Spectrometry for Ultrahigh-Throughput Analysis up to and Above 30Hz.
35. Rapid Model-Based Optimization of a Two-Enzyme System for Continuous Reductive Amination in Flow
36. Monoamine Oxidase (MAO-N) Biocatalyzed Synthesis of Indoles from Indolines Prepared via Photocatalytic Cyclization/Arylative Dearomatization
37. Natural Heterogeneous Catalysis with Immobilised Oxidase Biocatalysts
38. One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles
39. Enantioselective Synthesis of Chiral Vicinal Amino Alcohols Using Amine Dehydrogenases
40. Biocatalytic Oxidation in Continuous Flow for the Generation of Carbohydrate Dialdehydes
41. Selective Oxidation of N-Glycolylneuraminic Acid Using an Engineered Galactose Oxidase Variant
42. GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries
43. Technical Considerations for Scale-Up of Imine-Reductase-Catalyzed Reductive Amination: A Case Study
44. One-Pot Biocatalytic Synthesis of Substitutedd-Tryptophans from Indoles Enabled by an Engineered Aminotransferase
45. Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades
46. Biocatalysis Using Immobilized Enzymes in Continuous Flow for the Synthesis of Fine Chemicals
47. Chemoenzymatic Synthesis of Substituted Azepanes by Sequential Biocatalytic Reduction and Organolithium-Mediated Rearrangement
48. Monoamine Oxidase: Tunable Activity for Amine Resolution and Functionalization
49. A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases
50. Concurrent Biocatalytic Oxidation and C–C Bond Formation via Gold Catalysis: One-Pot Alkynylation of N-Alkyl Tetrahydroisoquinolines
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