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Your search keyword '"Valentina Sgarzani"' showing total 1 results
Start Over Author "Valentina Sgarzani" Publisher american chemical society (acs)
1 results on '"Valentina Sgarzani"'

1. Direct Access to Enantiomerically Enriched α-Amino Phosphonic Acid Derivatives by Organocatalytic Asymmetric Hydrophosphonylation of Imines

Author

Alfredo Ricci, Daniel Pettersen, Raquel P. Herrera, Francesco Fini, Luca Bernardi, Mauro Marcolini, and Valentina Sgarzani

Subjects
Phosphonic acid derivatives, chemistry.chemical_compound, Chemistry, Organic Chemistry, Imine, Enantioselective synthesis, Organic chemistry, Amine gas treating, General Medicine, Enantiomeric excess, Catalysis
Abstract

A simple and efficient organocatalytic enantioselective hydrophosphonylation of imines to enantiomerically enriched alpha-amino phosphonates is reported. By using 10 mol % of quinine as the catalyst in the enantioselective addition of diethyl phosphite to N-Boc protected imines, alpha-amino phosphonates are obtained in moderate to good yields and with up to 94% ee.

Published
2006
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