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1. The Emerging Importance of Autophagy in Pulmonary Diseases.

Author

Mizumura, Kenji, Cloonan, Suzanne M., Haspel, Jeffrey A., and Choi, Augustine M. K.

Subjects
*AUTOPHAGY, *CELL death, *IMMUNE response, *LUNG diseases, *CELLS
Abstract

The article discusses the evidence emerging for the role of autophagy and selective autophagy in cell survival, cell death, and immune and inflammatory response related to the pathogenesis of complex lung diseases. It discusses the principal components of the autophagic process. The dual nature of autophagy in the lung and the challenge posed by this duality for designing autophagy-based diagnostic and therapeutic targets in lung disease are also examined.

Published
2012
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