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B CLINICAL IMPLICATIONS: b Results from further studies like this will help personalize CPR to an individual's specific resuscitative needs rather than standardizing CPR to all patients. Future studies examining hemodynamic-directed CPR vs current CPR standards are needed to enhance the effective use of physiologic measures to improve resuscitation outcomes. [Extracted from the article]

B PURPOSE: b The delivery of cardiopulmonary resuscitation (CPR) with correct chest compression quality and ventilation rate is critical for patient survival. The American Heart Association adult advanced cardiac life support guidelines recommend a respiratory rate of 8-10 breaths per minute after advanced airway placement during CPR. We sought out to evaluate real-world guideline adherence to ventilation rate during CPR during in-hospital cardiac arrest. [Extracted from the article]

B PURPOSE: b Duration of cardiopulmonary resuscitation (CPR) is a major determinant of survival for cardiac arrest (CA). The average time to any diagnostic laboratory testing (serum labs, POC glucose, ABG, or VBG) was 13.8 (SD ± 13) minutes, which was performed in only 57% of cases. [Extracted from the article]

Though there have been limited studies assessing its impact, a single case report published in 2017 suggests that ECMO may enhance tissue oxygenation during cardiopulmonary resuscitation (CPR), a known correlate of survival with independent neurological function. B CONCLUSIONS: b ECMO-assisted CPR is associated with marked increases in brain oxygen delivery as evidenced through real-time cerebral oximetry monitoring. [Extracted from the article]

Overall, 77 (45.6%) achieved ROSC, however there were no differences in age among ROSC vs. no ROSC patients (71 v 68, p=0.3)or APACHE II scores (27 v 27, p=0.9). The mean Hb of those with ROSC was 11.7 g/dL (SD 3.3) versus 10.9 g/dL (SD 2.6) among those without ROSC (p<0.09), which represents approximately 10% difference in oxygen delivery. The mean Hb of VF/VT patients achieving ROSC was 12.5 g/dL (SD 2.4) v. 9.1 g/dL (SD 1.8) among those without ROSC (p=0.001). [Extracted from the article]

B PURPOSE: b A recent study examining in hospital cardiac arrest (IHCA) has indicated that the optimal duration of cardiopulmonary resuscitation (CPR) leading to the highest rates of return of spontaneous circulation (ROSC) and survival is 45 minutes. We compared the characteristics of IHCA events, CPR duration based on age, and examined the rates of ROSC and survival to discharge (sDC) at a large urban academic medical center. [Extracted from the article]

We measured the ETCO2 thresholds of 10, 20, 25, and 40 mmHg ETCO2 at t=0 (the first recording), 10, 15, and 20 minutes into CPR, as well as the average ETCO2 throughout CPR in subjects with ROSC vs. We also examined the utility of pre-specified thresholds of ETCO2 at pre-defined time points and found no differences in ETCO2 at t=0, 15 or 20 minutes of CPR between those with ROSC vs. [Extracted from the article]