1. Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduces caregivers’ fear of hypoglycemia and improves their well-being
- Author
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KidsAP Consortium, Ineke M. Pit-ten Cate, Roman Hovorka, Craig Kollman, Julia K. Mader, Charlotte Boughton, Janet M Allen, Alena Thiele, Maria Fritsch, Stéphane Roze, Julia Lawton, Judy Sibayan, Laura E. Bocchino, James Yong, Fiona M. Campbell, Sabine E. Hofer, Birgit Rami‐Merhar, Thomas M. Kapellen, Elke Fröhlich-Reiterer, Malgorzata E Wilinska, Julia Ware, Ajay Thankamony, Ulrike Schierloh, and Carine de Beaufort
- Subjects
Advanced and Specialized Nursing ,Endocrinology, Diabetes and Metabolism ,Internal Medicine - Abstract
OBJECTIVE To evaluate the impact of CamAPS FX hybrid closed-loop (HCL) automated insulin delivery in very young children with type 1 diabetes (T1D) on caregivers’ well-being, fear of hypoglycemia, and sleepiness. RESEARCH DESIGN AND METHODS We conducted a multinational, open-label, randomized crossover study. Children (age 1–7 years) with T1D received treatment for two 4-month periods in random order, comparing HCL with sensor augmented pump (control). At baseline and after each treatment period, caregivers were invited to complete World Health Organization–Five Well-Being Index, Hypoglycemia Fear Survey, and Epworth Sleepiness Scale questionnaires. RESULTS Caregivers of 74 children (mean ± SD age 5 ± 2 years and baseline HbA1c 7.3 ± 0.7%; 42% female) participated. Results revealed significantly lower scores for hypoglycemia fear (P < 0.001) and higher scores for well-being (P < 0.001) after HCL treatment. A trend toward a reduction in sleepiness score was observed (P = 0.09). CONCLUSIONS Our results suggest better well-being and less hypoglycemia fear in caregivers of very young children with T1D on CamAPS FX HCL.
- Published
- 2022
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