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The small current detection circuit is the core component of the accurate detection of the nanopore sensor. In this paper, a compact, low-noise, and high-speed trans-impedance amplifier is built for the nanopore detection system. The amplifier consists of two amplification stages. The first stage performs low-noise trans-impedance amplification by using ADA4530-1, which is a high-performance FET operational amplifier, and a high-ohm feedback resistor of 1 GΩ. The high pass shelf filter in the second stage recovers the higher frequency above the 3 dB cutoff in the first stage to extend the maximum bandwidth up to 50 kHz. The amplifier shows a low noise below sub-2 pA rms when tuned to have a bandwidth of around 5 kHz. It also guarantees a stable frequency response in the nanopore sensor. [ABSTRACT FROM AUTHOR]

This document is an erratum for an article titled "Low-noise and high-speed trans-impedance amplifier for nanopore sensor" published in the Review of Scientific Instruments. The erratum states that Figure 2(a) in the original article was adapted from Dr. Vadim Shlyonsky's design without proper citation or authorization. The erratum provides a table listing the components in the original article and their corresponding parts in Dr. Vadim Shlyonsky's design. The document also mentions that the authors referred to Dr. Vadim Shlyonsky's design to solve the problem of bandwidth expansion in their own design of a low-noise and high-speed trans-impedance amplifier for the nanopore sensor. [Extracted from the article]

The dielectric breakdown used to fabricate solid-state nanopores has separated the device from capital-intensive industries and has been widely adopted by various research teams, but there are still problems with low production efficiency and uncertain location. In this work, based on the transient breakdown phenomenon of nanofilms, a new type of dielectric breakdown apparatus for nanopore fabrication is reported. It integrates both nano-manipulation technology and dielectric breakdown nanopore fabrication technology. The nanometer distance detection method and circuit are introduced in detail. The generation principle and procedures of the transient high electric field are explained step by step. The characterization of the nanopores shows that this apparatus can fabricate sub-2 nm nanopores at a pre-located position. Besides, the nanopore diameter can be easily adjusted by setting the transient high electric field value. [ABSTRACT FROM AUTHOR]

A novel phase-type quantum-dot-array diffraction grating (QDADG) is reported. In contrast to an earlier amplitude-type QDADG [C. Wang et al., Rev. Sci. Instrum. 78, 053503 (2007)], the new phase-type QDADG would remove the zeroth order diffraction at some certain wavelength, as well as suppressing the higher-order diffractions. In this paper, the basic concept, the fabrication, the calibration techniques, and the calibration results are presented. Such a grating can be applied in the research fields of beam splitting, laser probe diagnostics, and so on. [ABSTRACT FROM AUTHOR]

A new dispersive element named as quantum-dot-array diffraction grating [L. F. Cao, China patent No. 200410081499 (August 10, 2004)] for visible light has been developed and characterized experimentally. A large number of quantum dots distributed on a substrate as sinusoidal function can be used to diffract x rays without higher-order diffraction. The experimental patterns show that the higher-order diffractions which inevitably exist in the spectrum recorded using traditional diffraction gratings can be eliminated effectively by this newly designed element. It indicates that quantum-dot-array diffraction grating could be an attractive alternative of presently used diffraction grating in soft x-ray spectroscopy application to get rid of the higher-order diffraction distortions. [ABSTRACT FROM AUTHOR]