1. Incidence of schizophrenia in a nationwide cohort of patients with type 1 diabetes mellitus.
- Author
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Juvonen H, Reunanen A, Haukka J, Muhonen M, Suvisaari J, Arajärvi R, Partonen T, and Lönnqvist J
- Subjects
- Age of Onset, Aged, Cohort Studies, Comorbidity, Female, Finland epidemiology, Follow-Up Studies, Humans, Incidence, Longitudinal Studies, Male, Middle Aged, Registries statistics & numerical data, Risk, Sex Distribution, Diabetes Mellitus, Type 1 epidemiology, Schizophrenia epidemiology
- Abstract
Context: Patients with schizophrenia have an increased risk of type 2 diabetes mellitus. However, very few studies have dealt with the association of type 1 diabetes and schizophrenia. Preliminary evidence points to a possible inverse association., Objective: To investigate the incidence of schizophrenia in a nationwide cohort of patients with type 1 diabetes born in 1950 through 1959 in Finland., Design: A cohort study of individuals born in 1950 through 1959 with a follow-up of 1969 through 1991., Setting: Finland., Patients: All individuals born in 1950 through 1959 with type 1 diabetes were identified through nationwide registers. The incidence of schizophrenia until 1992 among the total 1950-1959 cohort and in individuals with type 1 diabetes was calculated using information from 3 health care registers., Main Outcome Measure: Incidence of schizophrenia., Results: The incidence of schizophrenia was 0.21 per 10 000 person-years in the group with type 1 diabetes and 0.56 per 10 000 person-years in the group without type 1 diabetes (P < .001)., Conclusion: The incidence of schizophrenia is decreased in patients with type 1 diabetes.
- Published
- 2007
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