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The many-particle time-dependent Schr\"odinger equation is derived using the principle of minimum Fisher information. This application of information theory leads to a physically well motivated derivation of the Schr\"odinger equation, which distinguishes between subjective and objective elements of the theory.

When interactions are turned off, the theory of interacting quantum and classical ensembles due to Hall and Reginatto is shown to suffer from a nonlocal signaling effect that is effectively action at a distance. This limits the possible applicability of the theory. In its present form, it is restricted to those situations in which interactions are always on, such as classical gravity interacting with quantized matter., Comment: 3 pages, no figures