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Your search keyword '"LeJeune, Wanda S"' showing total 2 results
Start Over Author "LeJeune, Wanda S" Publisher american physiological society
2 results on '"LeJeune, Wanda S"'

1. TNF-alpha causes reversible in vivo systemic vascular barrier dysfunction via NO-dependent and -independent mechanisms

Author

Worrall, Neil K., Chang, Kathy, LeJeune, Wanda S., Misko, Thomas P., Sullivan, Patrick M., Ferguson, T. Bruce Jr., and Williamson, Joseph R.

Subjects
Tumor necrosis factor -- Physiological aspects, Blood-brain barrier -- Research, Nitric oxide -- Research, Biological sciences
Abstract

Research shows that biochemical tumor necrosis factor-alpha interacts with nitric oxide (NO) to damage the blood-brain vascular barrier mechanism. Endothelial barrier integrity does not occur in the presence of an NO synthase enzyme inhibitor. Experiments to establish vascular barrier dysfunction in various tissues such as lung, liver and sciatic nerge are described.

Published
1997

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