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Your search keyword '"Wagner, Daniel R."' showing total 4 results
Start Over Author "Wagner, Daniel R." Publisher american physiological society
4 results on '"Wagner, Daniel R."'

1. Differential regulation of cardiac expression of IL-6 and TNF-alpha by A2- and A3-adenosine receptors

Author

Wagner, Daniel R., Kubota, Toru, Sanders, Virginia J., McTiernan, Charles F., and Feldman, Arthur M.

Subjects
Congestive heart failure -- Research, Interleukin-6 -- Research, Tumor necrosis factor -- Research, Cytokines -- Research, Adenosine -- Research, Biological sciences
Abstract

Research was conducted to examine the effect of adenosine and its three cardiac receptors on the expression of interleukin (IL)-6 and IL-1-beta in isolated cardiomyocytes, rat papillary muscles and trabecular muscles derived from human patients with advanced cardiomyopathy. Results indicate that A2 and A3 receptors differentially regulate cardiac expression of tumor necrosis factor-alpha and IL-6. It was also shown that rat cardiomyocytes and the failing human heart respond differently to adenosine.

Published
1999

4. Differential regulation of cardiac expression of IL-6 and TNF-... by A... and A...-adenosine...

Author

Wagner, Daniel R. and Kubota, Toru

Subjects
*INTERLEUKIN-6, *HEART cells, *CARDIOMYOPATHIES, *PHYSIOLOGY
Abstract

Focuses on a study which examined the effect of adenosine and its three cardiac receptors on the expression of interleukin-6 and interleukin-1beta in isolated rat cardiomyocytes and trabecular muscles obtained from patients with cardiomyopathy. Background on proinflammatory cytokines; Materials and methods; Results and discussion.

Published
1999
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