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This commentary refers to the article "Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial," by G-M. Santos, J. Ikeda, P. Coffin and colleagues, that was published within the issue. Topics discussed include efficacy and tolerability of topiramate and other medications for the treatment of alcohol use disorder (AUD), clinical practice guidelines for the pharmacological treatment of AUD, and side effects from naltrexone.

A letter to the editor is presented in response to the article about dignity therapy in a male patient with severe alcohol use disorders.

The article presents a case study of a 55-year-old man with schizoaffective disorder and multiple psychiatric hospitalizations. The patient undergoes dignity therapy to tell his life story to his children. Following the therapy, he reported that the therapy had restored hope and enabled him to communicate better with his children. It argues that the therapy helped a patient with a debilitating illness face a negative life event.