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Your search keyword '"Drug-Related Side Effects and Adverse Reactions diagnostic imaging"' showing total 2 results
Start Over Descriptor "Drug-Related Side Effects and Adverse Reactions diagnostic imaging" Publisher american roentgen ray society
2 results on '"Drug-Related Side Effects and Adverse Reactions diagnostic imaging"'

1. A Review of the Mechanisms and Clinical Implications of Precision Cancer Therapy-Related Toxicity: A Primer for the Radiologist.

Author

Thomas R, Howard SA, Laferriere SL, and Braschi-Amirfarzan M

Subjects
Humans, Drug-Related Side Effects and Adverse Reactions diagnostic imaging, Immunotherapy adverse effects, Molecular Targeted Therapy adverse effects, Neoplasms drug therapy, Precision Medicine adverse effects
Abstract

OBJECTIVE. The purpose of this review is to elucidate the mechanisms, types, and clinical significance of molecular targeted therapy (MTT) and immune checkpoint inhibitors (ICIs) and their related toxicity, emphasizing the radiologic manifestations. CONCLUSION. The related toxicities of MTT and ICIs can have acute, recurrent, chronic, and delayed presentations. These toxicities may serve as markers of response and survival. By understanding the clinical significance of drug toxicities, radiologists can play an important role in personalized cancer therapy.

Published
2020
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2. Radiologic aspects of immune-related tumor response criteria and patterns of immune-related adverse events in patients undergoing ipilimumab therapy.

Author

O'Regan KN, Jagannathan JP, Ramaiya N, and Hodi FS

Subjects
Drug-Related Side Effects and Adverse Reactions immunology, Humans, Ipilimumab, Melanoma immunology, Melanoma pathology, Neoplasm Staging, Skin Neoplasms immunology, Skin Neoplasms pathology, Antibodies, Monoclonal adverse effects, Drug-Related Side Effects and Adverse Reactions diagnostic imaging, Immunotherapy adverse effects, Melanoma drug therapy, Skin Neoplasms drug therapy, Tomography, X-Ray Computed
Abstract

Objective: The objective of this article is to illustrate examples of radiologic immune-related response criteria and toxicity in patients with advanced melanoma treated with the immunotherapeutic agent ipilimumab., Conclusion: Novel immune-related tumor response criteria should be applied to patients undergoing therapy with ipilimumab for advanced melanoma. Ipilimumab also produces a spectrum of immune-related adverse effects that can be recognized radiologically.

Published
2011
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