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Start Over Author "Song, Jingmei" Publisher american society for clinical investigation
1 results on '"Song, Jingmei"'

1. Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in LDLR-/- mice

Author

Zhao, Bin, Song, Jingmei, Chow, Woon N., Clair, Richard W. St., Rudel, Lawrence L., and Ghosh, Shobha

Subjects
Atherosclerosis -- Genetic aspects, Atherosclerosis -- Research, Hydrolases -- Health aspects, Hydrolases -- Research, Enzymes -- Health aspects, Enzymes -- Research, Macrophages -- Genetic aspects, Macrophages -- Health aspects, Macrophages -- Research
Abstract

Accumulation of cholesteryl esters (CEs) in macrophage foam cells, central to atherosclerotic plaque formation, occurs as a result of imbalance between the cholesterol influx and efflux pathways. While the uptake, [...]

Published
2007

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