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Start Over Author "Cooksley, Clare" Publisher american society for microbiology
2 results on '"Cooksley, Clare"'

2. Regulation of neurotoxin production and sporulation by a putative agrBD signaling system in proteolytic Clostridium botulinum

Author

Cooksley, Clare M., Davis, Ian J., Winzer, Klaus, Weng C. Chan, Peck, Michael W., and Minton, Nigel P.

Subjects
Spores (Bacteria) -- Research, Clostridium botulinum -- Genetic aspects, Clostridium botulinum -- Physiological aspects, Neurotoxic agents -- Research, Quorum sensing -- Usage, Biological sciences
Abstract

The characterization of two distinct agr loci from all group I strains of Clostridium botulinum ATCC 3502 and of their homologues in a close relative, Clostridium sporogenes NCIMB 10696 is reported. Compared to the wild-type strains, C. botulinum strains exhibited remarkably reduced sporulation and also reduced production of neurotoxin for C. botulinum indicated that both phenotypes are controlled by quorum sensing.

Published
2010

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