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Your search keyword '"Geoffrey Paul Smith"' showing total 2 results
Start Over Author "Geoffrey Paul Smith" Publisher american society for microbiology
2 results on '"Geoffrey Paul Smith"'

1. Characterization of a Verocytotoxin-Producing Enteroaggregative Escherichia coli Serogroup O111:H21 Strain Associated with a Household Outbreak in Northern Ireland

Author

Kathie Grant, Timothy J. Dallman, Marie Anne Chattaway, Claire Jenkins, David Finlay, Brendan O'Brien, and Geoffrey Paul Smith

Subjects
Male, Microbiology (medical), Serotype, Prophages, Verocytotoxin, Northern Ireland, Biology, medicine.disease_cause, Coliphages, Shiga Toxin 2, Disease Outbreaks, Microbiology, chemistry.chemical_compound, Escherichia coli, medicine, Animals, Cluster Analysis, Humans, Serotyping, Escherichia coli Infections, Prophage, Family Health, Family Characteristics, Molecular Epidemiology, Shiga-Toxigenic Escherichia coli, Strain (chemistry), Outbreak, Bacteriology, Virology, chemistry, Child, Preschool, Enteroaggregative Escherichia coli, Multilocus sequence typing, Female, Multilocus Sequence Typing, Plasmids
Abstract

A strain of Escherichia coli O111:H21 recently isolated in the United Kingdom harbored the phage-encoded vtx2c gene and the aggregative adherence plasmid. Although exhibiting the same pathogenic profile as the E. coli O104:H4 strain linked to the outbreak in Germany, there were important differences in strain characteristics and in the epidemiological setting.

Published
2012
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2. Rapid Whole-Genome Sequencing for Investigation of a Suspected Tuberculosis Outbreak

Author

M. Estée Török, Bernadette Nazareth, Julian Parkhill, Geoffrey Paul Smith, Josephine M. Bryant, Sian V. Stinchcombe, Sharon J. Peacock, Sandra Reuter, Claudio U. Köser, Stephen D. Bentley, and Matthew J. Ellington

Subjects
Microbiology (medical), Adult, Male, medicine.medical_specialty, Tuberculosis, education, Drug resistance, Biology, Southeast asian, Disease Outbreaks, Mycobacterium tuberculosis, Young Adult, Epidemiology, medicine, Humans, Phylogeny, Whole genome sequencing, Transmission (medicine), Outbreak, Mycobacteriology and Aerobic Actinomycetes, Sequence Analysis, DNA, medicine.disease, biology.organism_classification, Virology, United Kingdom, Genome, Bacterial
Abstract

Two Southeast Asian students attending the same school in the United Kingdom presented with pulmonary tuberculosis. An epidemiological investigation failed to link the two cases, and drug resistance profiles of the Mycobacterium tuberculosis isolates were discrepant. Whole-genome sequencing of the isolates found them to be genetically identical, suggesting a missed transmission event.

Published
2013

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